Regulation of renal CYP4A expression and 20-HETE synthesis by nitric oxide in pregnant rats.
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Cytochrome P450 ω-Hydroxylases in Inflammation and CancerCyclooxygenase- and cytochrome P450-derived eicosanoids in stroke20-hydroxy-5,8,11,14-eicosatetraenoic acid mediates endothelial dysfunction via IkappaB kinase-dependent endothelial nitric-oxide synthase uncouplingA synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in ratsRenal function and vasomotor activity in mice lacking the Cyp4a14 gene.Role of atrial natriuretic peptide in mediating the blood pressure-independent natriuresis elicited by systemic inhibition of nitric oxideContribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats.Piroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxide20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats.20-HETE-mediated cytotoxicity and apoptosis in ischemic kidney epithelial cells.Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shockNS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite.Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production.Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic TargetExpression of CYP 4A ω-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes.Long-term modifications of blood pressure in normotensive and spontaneously hypertensive rats by gene delivery of rAAV-mediated cytochrome P450 arachidonic acid hydroxylase.Contribution of cytochrome P450 metabolites of arachidonic acid to hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME.Renal cytochrome P450 as a determinant of impaired natriuresis by PPAR-gamma ligands in ovariectomized obese rats.
P2860
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P2860
Regulation of renal CYP4A expression and 20-HETE synthesis by nitric oxide in pregnant rats.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@en
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@nl
type
label
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@en
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@nl
prefLabel
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@en
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@nl
P2093
P2860
P1476
Regulation of renal CYP4A expr ...... nitric oxide in pregnant rats.
@en
P2093
Alberto Nasjletti
Barbara A Zand
Hsin-Hsin Chang
Jishi Wang
Miao Jiang
Michal Laniado-Schwartzman
Mong-Heng Wang
P2860
P304
P356
10.1152/AJPRENAL.00065.2003
P577
2003-04-08T00:00:00Z