Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.
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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1Activation of the caspase-8/Bid and Bax pathways in aspirin-induced apoptosis in gastric cancerTaxol induces caspase-10-dependent apoptosisGefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimeticsFTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levelsCompound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells.Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.Jacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins.Identification of subtilase cytotoxin (SubAB) receptors whose signaling, in association with SubAB-induced BiP cleavage, is responsible for apoptosis in HeLa cells.Survival factor withdrawal-induced apoptosis of TF-1 cells involves a TRB2-Mcl-1 axis-dependent pathway.Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.Regulation of apoptosis proteins in cancer cells by ubiquitin.Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling.Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells.Sheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins.Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.Detergent-activated BAX protein is a monomer.Chlamydia trachomatis infection inhibits both Bax and Bak activation induced by staurosporineComplementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cellsInduction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells.Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells.Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib.Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells.Combined proteasome and Bcl-2 inhibition stimulates apoptosis and inhibits growth in EBV-transformed lymphocytes: a potential therapeutic approach to EBV-associated lymphoproliferative diseases.Overexpression of Bax induces apoptosis and enhances drug sensitivity of hepatocellular cancer-9204 cells.Long-acting beta2-adrenergic formoterol and salmeterol induce the apoptosis of B-chronic lymphocytic leukaemia cells.The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis.Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cellsEndogenous Noxa Determines the Strong Proapoptotic Synergism of the BH3-Mimetic ABT-737 with Chemotherapeutic Agents in Human Melanoma Cells.Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.Inhibition of Akt/GSK3beta signalling pathway by Legionella pneumophila is involved in induction of T-cell apoptosis.Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1.CDDO induces apoptosis via the intrinsic pathway in lymphoid cells.AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway.
P2860
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P2860
Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
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2003年学术文章
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2003年學術文章
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name
Conformational change and mito ...... ic lymphocytic leukemic cells.
@en
Conformational change and mito ...... ic lymphocytic leukemic cells.
@nl
type
label
Conformational change and mito ...... ic lymphocytic leukemic cells.
@en
Conformational change and mito ...... ic lymphocytic leukemic cells.
@nl
prefLabel
Conformational change and mito ...... ic lymphocytic leukemic cells.
@en
Conformational change and mito ...... ic lymphocytic leukemic cells.
@nl
P2093
P2860
P356
P1433
P1476
Conformational change and mito ...... nic lymphocytic leukemic cells
@en
P2093
Gerald M Cohen
Grant Dewson
Jason B Almond
Roger T Snowden
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206326
P407
P50
P577
2003-05-01T00:00:00Z