Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression.
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Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switchNew insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancerA para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducerPreclinical evaluation of the proteasome inhibitor bortezomib in cancer therapyThe mitochondrial permeability transition pore and cancer: molecular mechanisms involved in cell deathModulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathwaysPathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Gene Expression Analysis of the 26S Proteasome Subunit PSMB4 Reveals Significant Upregulation, Different Expression and Association with Proliferation in Human Pulmonary Neuroendocrine TumoursDefective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophyMono- or double-site phosphorylation distinctly regulates the proapoptotic function of BaxAspirin delimits platelet life span by proteasomal inhibitionThe role of proteasome inhibition in the treatment of malignant and non-malignant hematologic disorders.Progressively impaired proteasomal capacity during terminal plasma cell differentiation.Bax-dependent regulation of Bak by voltage-dependent anion channel 2.Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells.Role of proteasomes in disease.The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaBPlatinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibitionHeat shock protein 70 (hsp70) as an emerging drug target.Ubiquitination by SAG regulates macrophage survival/death and immune response during infection.Targeting the ubiquitin-proteasome pathway with inorganic compounds to fight cancer: a challenge for the future.Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition poresRegulation of apoptosis by fau revealed by functional expression cloning and antisense expression.Synthesis of (2R, 3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, and evaluation of its proteasome inhibitory activities.Gentamicin causes apoptosis at low concentrations in renal LLC-PK1 cells subjected to electroporation.HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivoP53: an ubiquitous target of anticancer drugs.Murraya koenigii leaf extract inhibits proteasome activity and induces cell death in breast cancer cells.Induction of tumor cell apoptosis by a proteasome deubiquitinase inhibitor is associated with oxidative stressActivation of GluR6-containing kainate receptors induces ubiquitin-dependent Bcl-2 degradation via denitrosylation in the rat hippocampus after kainate treatmentMuscle-specific overexpression of NCOATGK, splice variant of O-GlcNAcase, induces skeletal muscle atrophy.Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system.Immunohistochemical expression of apoptosis regulators in squamous cell carcinoma of the cervix and their association with human papillomavirus 16/18 subtypes.On the role of proteasomes in cell biology and proteasome inhibition as a novel frontier in the development of immunosuppressants.Mechanisms of MHC class I-restricted antigen presentation.Cytosolic Hsp60 can modulate proteasome activity in yeastThe EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans
P2860
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P2860
Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Bax degradation by the ubiquit ...... umor survival and progression.
@ast
Bax degradation by the ubiquit ...... umor survival and progression.
@en
type
label
Bax degradation by the ubiquit ...... umor survival and progression.
@ast
Bax degradation by the ubiquit ...... umor survival and progression.
@en
prefLabel
Bax degradation by the ubiquit ...... umor survival and progression.
@ast
Bax degradation by the ubiquit ...... umor survival and progression.
@en
P2860
P356
P1476
Bax degradation by the ubiquit ...... umor survival and progression.
@en
P2860
P304
P356
10.1073/PNAS.070047997
P407
P577
2000-04-01T00:00:00Z