AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability. - Wikidata - wikimedia - TriplyDB

AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.

AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.

http://www.wikidata.org/entity/Q44436375

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Glucose stimulates cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes The AMPK signalling pathway coordinates cell growth, autophagy and metabolism AMPK and PPARdelta agonists are exercise mimetics AMPK as a potential anticancer target - friend or foe?Nuclear receptors and AMPK: resetting metabolism AMPK: a cellular metabolic and redox sensor. A minireview Cellular and molecular mechanisms of metformin: an overview Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4 : DIABETES GENE PRODUCT The nuclear pore complex mediates binding of the Mig1 repressor to target promoters Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids Molecular cloning and promoter analysis of downregulated in adenoma (DRA)Regulation of rat hepatic L-pyruvate kinase promoter composition and activity by glucose, n-3 polyunsaturated fatty acids, and peroxisome proliferator-activated receptor-alpha agonist Hepatocyte nuclear factor-4alpha contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase AMP-activated protein kinase is a key intermediary in GnRH-stimulated LHβ gene transcription Mapping of HNF4alpha target genes in intestinal epithelial cells Hepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytes Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha Nuclear receptor HNF4α binding sequences are widespread in Alu repeats Transforming growth factor-β1 suppresses hepatitis B virus replication by the reduction of hepatocyte nuclear factor-4α expression.LDL-cholesterol reduction in patients with hypercholesterolemia by modulation of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase Increased DNA methyltransferase 3b (Dnmt3b)-mediated CpG island methylation stimulated by oxidative stress inhibits expression of a gene required for neural tube and neural crest development in diabetic pregnancy.HNF4α--role in drug metabolism and potential drug target?Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.Sodium arsenite induces orphan nuclear receptor SHP gene expression via AMP-activated protein kinase to inhibit gluconeogenic enzyme gene expression.Prevention of diabetes-promoted colorectal cancer by (n-3) polyunsaturated fatty acids and (n-3) PUFA mimetic.Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway.AMPK in cardiovascular health and disease.Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells Quantitative analysis of cytokine-induced hepatocyte nuclear factor-4α phosphorylation by mass spectrometry.Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases Quercetin represses apolipoprotein B expression by inhibiting the transcriptional activity of C/EBPβ.The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression.AMP-activated protein kinase mediates effects of oxidative stress on embryo gene expression in a mouse model of diabetic embryopathy.Thyroid-Stimulating Hormone Increases HNF-4α Phosphorylation via cAMP/PKA Pathway in the Liver Gene Network Analysis of Glucose Linked Signaling Pathways and Their Role in Human Hepatocellular Carcinoma Cell Growth and Survival in HuH7 and HepG2 Cell Lines.Identification of the Flavonoid Luteolin as a Repressor of the Transcription Factor Hepatocyte Nuclear Factor 4α Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation.

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P2860

AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.

http://www.wikidata.org/entity/Q44436375

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

@zh

2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh-hant

name

AMP-activated protein kinase r ...... decreasing protein stability.

@en

AMP-activated protein kinase r ...... decreasing protein stability.

@nl

type

label

AMP-activated protein kinase r ...... decreasing protein stability.

@en

AMP-activated protein kinase r ...... decreasing protein stability.

@nl

prefLabel

AMP-activated protein kinase r ...... decreasing protein stability.

@en

AMP-activated protein kinase r ...... decreasing protein stability.

@nl

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P1433

Journal of Biological Chemistry

P1476

AMP-activated protein kinase r ...... decreasing protein stability.

@en

P2093

Todd Leff

http://www.w3.org/2001/XMLSchema#string

Usha S Varanasi

http://www.w3.org/2001/XMLSchema#string

Wenbo Yang

http://www.w3.org/2001/XMLSchema#string

Yu Holly Hong

http://www.w3.org/2001/XMLSchema#string

P2860

Mitogen-activated protein kinase regulates transcription of the ApoCIII gene. Involvement of the orphan nuclear receptor HNF4

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene

Recruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

P304

27495-27501

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scholarly article

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10.1074/JBC.M304112200

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30

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278

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2003-05-09T00:00:00Z

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10766562

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12740371

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