Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.
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Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factorsPregnane X receptor and natural products: beyond drug-drug interactionsUse of transgenic mice in UDP-glucuronosyltransferase (UGT) studiesClinical application of transcriptional activators of bile salt transporters.The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Adaptive hepatic and intestinal alterations in mice after deletion of NADPH-cytochrome P450 Oxidoreductase (Cpr) in hepatocytesSucralose, a synthetic organochlorine sweetener: overview of biological issuesRole of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice.Severe diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice.Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liverThe pregnane X receptor in tuberculosis therapeutics.Regulation of hepatic phase II metabolism in pregnant micePXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.Expression of the PXR gene in various types of cancer and drug resistanceNuclear receptors as drug targets in cholestatic liver diseases.Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes.Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid.Mechanism of gender-divergent UDP-glucuronosyltransferase mRNA expression in mouse liver and kidney.Nuclear receptors as therapeutic targets in cholestatic liver diseases.Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.A Toxicologist's Guide to the Preclinical Assessment of Hepatic Microsomal Enzyme Induction.Advantages of cell-based high-volume screening assays to assess nuclear receptor activation during drug discovery.New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear faIn vivo acute exposure to polychlorinated biphenyls: effects on free and total thyroxine in rats.Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.Effects of chronic exposure to triclosan on reproductive and thyroid endpoints in the adult Wistar female rat.Role of CYP3A in Oral Contraceptives Clearance.Schisandrol B protects against cholestatic liver injury through pregnane X receptors.Thyroid hormone-dependent gene expression as a biomarker of short-term 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) exposure in European common frog (Rana temporaria) tadpoles.
P2860
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P2860
Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@en
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@nl
type
label
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@en
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@nl
prefLabel
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@en
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@nl
P2093
P356
P1476
Nuclear receptor, pregname X r ...... enolone-16 alpha-carbonitrile.
@en
P2093
Chuan Chen
Curtis D Klaassen
Jeff L Staudinger
P304
P356
10.1124/DMD.31.7.908
P577
2003-07-01T00:00:00Z