Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.
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Hormone-sensitive lipase knockoutsRegulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise.Genetic variance in the adiponutrin gene family and childhood obesity.Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanismsAltered desaturation and elongation of fatty acids in hormone-sensitive lipase null miceNeural innervation of white adipose tissue and the control of lipolysis.Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency.Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.Genetic covariance between gamma-glutamyl transpeptidase and fatty liver risk factors: role of beta2-adrenergic receptor genetic variation in twins.Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.Adipose-selective overexpression of ABHD5/CGI-58 does not increase lipolysis or protect against diet-induced obesity.Hormone-sensitive lipase--new roles for an old enzyme.FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signalingLIPE C-60G influences the effects of physical activity on body fat and plasma lipid concentrations: the Quebec Family Study.Biochemistry and pathophysiology of intravascular and intracellular lipolysis.Altered expression of genes involved in lipid metabolism in obese subjects with unfavourable phenotype.Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity.Triglyceride lipases alter fuel metabolism and mitochondrial gene expression.Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.Targeting fatty acid metabolism to improve glucose metabolism.Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism.Short photoperiod reverses obesity in Siberian hamsters via sympathetically induced lipolysis and Browning in adipose tissue.Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2.Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-activated receptor alpha deficiency.The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-alpha in 3T3-L1 adipocytes and is a target for transactivation by PPARgamma.Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN.Effects of hormone-sensitive lipase disruption on cardiac energy metabolism in response to fasting and refeeding.A novel hormone-sensitive lipase isoform expressed in pancreatic beta-cells.Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes.Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice.Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice.The Testicular Form of Hormone-sensitive Lipase HSLtesConfers Rescue of Male Infertility in HSL-deficient Mice
P2860
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P2860
Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.
description
2003 nî lūn-bûn
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2003年の論文
@ja
2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
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@yue
2003年學術文章
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name
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@en
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@nl
type
label
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@en
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@nl
prefLabel
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@en
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@nl
P2093
P50
P356
P1476
Hormone-sensitive lipase null ...... s insulin secretion is intact.
@en
P2093
Cecilia Holm
Cecilia Lundberg
Frank Sundler
Henrik Galbo
Juan Antonio Contreras
Kristoffer Ström
Maria Sörhede-Winzell
Peter Arner
P304
36380-36388
P356
10.1074/JBC.M213032200
P407
P577
2003-06-30T00:00:00Z