Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase.
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Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363EHD1 regulates cholesterol homeostasis and lipid droplet storageMacrophage cholesteryl ester mobilization and atherosclerosisImproved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue.Macrophage cholesterol homeostasis and metabolic diseases: critical role of cholesteryl ester mobilization.Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic miceHormone-sensitive lipase--new roles for an old enzyme.Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice.Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies.Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencingRole of Kir2.1 in human monocyte-derived foam cell maturation.Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol AccumulationCarboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4α and Protects Against Alcohol- and MCD diet-induced Liver Injury.Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages.Lipid homeostasis and the formation of macrophage-derived foam cells in atherosclerosis.Balancing the fat: lipid droplets and human disease.Carboxylesterases in lipid metabolism: from mouse to human.Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading.Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness.Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.Lysosomes, cholesterol and atherosclerosis.Attenuation of adipocyte triacylglycerol hydrolase activity decreases basal fatty acid efflux.Development of mannose functionalized dendrimeric nanoparticles for targeted delivery to macrophages: use of this platform to modulate atherosclerosis.Study of ATP-binding cassette transporter A1 (ABCA1)-mediated cellular cholesterol efflux in diabetic golden hamsters.Sterol carrier protein-2 deficiency attenuates diet-induced dyslipidemia and atherosclerosis in mice
P2860
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P2860
Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@en
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@nl
type
label
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@en
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@nl
prefLabel
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@en
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@nl
P2093
P2860
P1476
Mobilization of cytoplasmic CE ...... e cholesteryl ester hydrolase.
@en
P2093
Lawrence L Rudel
Richard W St Clair
Shobha Ghosh
P2860
P304
P356
10.1194/JLR.M300162-JLR200
P577
2003-07-01T00:00:00Z