The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis.
about
PrionsMicrodissection: a method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesisImplications of prion polymorphismsTrans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactorPK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrPProtein folding pathology in domestic animals.Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathyBiochemical properties of highly neuroinvasive prion strainsDefining the conformational features of anchorless, poorly neuroinvasive prionsPost-translational modifications in PrP expand the conformational diversity of prions in vivoDistinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.No major change in vCJD agent strain after secondary transmission via blood transfusionTwo prion-inducing regions of Ure2p are nonoverlapping.A new method for the characterization of strain-specific conformational stability of protease-sensitive and protease-resistant PrPSc.Types and Strains: Their Essential Role in Understanding Protein Aggregation in Neurodegenerative Diseases.Species-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence.Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp.Coinfecting prion strains compete for a limiting cellular resource.Spiroplasma sp. 16S rDNA in Creutzfeldt-Jakob disease and scrapie as shown by PCR and DNA sequence analysis.Intracerebral distribution of the abnormal isoform of the prion protein in sporadic Creutzfeldt-Jakob disease and fatal insomnia.There is no safe dose of prions.Strain specific resistance to murine scrapie associated with a naturally occurring human prion protein polymorphism at residue 171.Atypical scrapie isolates involve a uniform prion species with a complex molecular signature.Sex effects in mouse prion disease incubation time.A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes.Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease.Prion strain interactions are highly selective.Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease.Propagation of RML prions in mice expressing PrP devoid of GPI anchor leads to formation of a novel, stable prion strainIn vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation.The [URE3] prion is not conserved among Saccharomyces speciesIdentification of inter-species transmission of prion strains.Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease.Experimental infection of meadow voles (Microtus pennsylvanicus) with sheep scrapiePrion strain-dependent differences in conversion of mutant prion proteins in cell culture.The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPScEpigenetic dominance of prion conformers.Prion infection of mouse brain reveals multiple new upregulated genes involved in neuroinflammation or signal transduction.Strain fidelity of chronic wasting disease upon murine adaptation.Tracking protein aggregate interactions.
P2860
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P2860
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
The disease characteristics of ...... host control of pathogenesis.
@en
The disease characteristics of ...... host control of pathogenesis.
@nl
type
label
The disease characteristics of ...... host control of pathogenesis.
@en
The disease characteristics of ...... host control of pathogenesis.
@nl
prefLabel
The disease characteristics of ...... host control of pathogenesis.
@en
The disease characteristics of ...... host control of pathogenesis.
@nl
P2093
P1476
The disease characteristics of ...... host control of pathogenesis.
@en
P2093
Dickinson AG
McConnell I
P304
P356
10.1099/0022-1317-72-3-595
P407
P478
72 ( Pt 3)
P577
1991-03-01T00:00:00Z