Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis. - Wikidata - wikimedia - TriplyDB

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

http://www.wikidata.org/entity/Q44557964

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Response gene to complement 32, a novel hypoxia-regulated angiogenic inhibitor Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis The STATs in cell stress-type responses The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation MicroRNA-93 controls perfusion recovery after hindlimb ischemia by modulating expression of multiple genes in the cell cycle pathway IGF-I activates PKB and prevents anoxic apoptosis in Achilles tendon cells.The role of endothelial cell apoptosis in inflammatory and immune diseases.Enhanced translation of heme oxygenase-2 preserves human endothelial cell viability during hypoxia p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death.Overexpression of GD3 synthase induces apoptosis of vascular endothelial ECV304 cells through downregulation of Bcl-2.Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1 Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2 Role of nitric oxide in placental vascular development and function.Three-dimensional cell grafting enhances the angiogenic efficacy of human umbilical vein endothelial cells.Vessel network formation in response to intermittent hypoxia is frequency dependent Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury Ischemia-reperfusion and cardioprotection: a delicate balance between reactive oxygen species generation and redox homeostasis.Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and hypoxia Dorsal column sensory axons degenerate due to impaired microvascular perfusion after spinal cord injury in rats RGS5, a hypoxia-inducible apoptotic stimulator in endothelial cells.Hypoxia-regulated angiogenic inhibitors.Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis.Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis.Insulin Receptor Substrate-1 Activation Mediated p53 Downregulation Protects Against Hypoxic-Ischemia in the Neonatal Brain.A VEGF/JAK2/STAT5 axis may partially mediate endothelial cell tolerance to hypoxia.Genome-wide analysis of p53 under hypoxic conditions.Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells.p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.Involvement of oxidative stress and caspase-3 in cortical infarction after photothrombotic ischemia in mice.Negative feedback for endothelial apoptosis: a potential physiological role for fibroblast growth factor.Comparison of effects of epigallocatechin-3-gallate on hypoxia injury to human umbilical vein, RF/6A, and ECV304 cells induced by Na(2)S(2)O(4).Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes.Peg3/Pw1 is involved in p53-mediated cell death pathway in brain ischemia/hypoxia.Hypoxia potentiates nitric oxide-mediated apoptosis in endothelial cells via peroxynitrite-induced activation of mitochondria-dependent and -independent pathways.Hypoxia upregulates Bcl-2 expression and suppresses interferon-gamma induced antiangiogenic activity in human tumor derived endothelial cells.Hypoxia-inducible factor-1alpha induces cell cycle arrest of endothelial cells.Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis.Whole-genome de novo sequencing reveals unique genes that contributed to the adaptive evolution of the Mikado pheasant.Obstructive Sleep Apnea: From Intermittent Hypoxia to Cardiovascular Complications via Blood Platelets

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Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

http://www.wikidata.org/entity/Q44557964

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

@zh-my

1999年学术文章

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1999年學術文章

@yue

1999年學術文章

@zh-hant

name

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

@en

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

@nl

type

label

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

@en

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

@nl

prefLabel

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

@en

Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

@nl

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JBC.274.12.8039

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Journal of Biological Chemistry

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Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis.

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A Karsan

http://www.w3.org/2001/XMLSchema#string

A Stempien-Otero

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C J Cornejo

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H Xiang

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J Harlan

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M Kay

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R S Morrison

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R Winn

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T Eunson

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P2860

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

p53, the cellular gatekeeper for growth and division

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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8039-8045

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