Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model.
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3D quantitative imaging of unprocessed live tissue reveals epithelial defense against bacterial adhesion and subsequent traversal requires MyD88Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversalRNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalizationThe galU Gene of Pseudomonas aeruginosa is required for corneal infection and efficient systemic spread following pneumonia but not for infection confined to the lung.The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells.Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones.Activities of Pseudomonas aeruginosa effectors secreted by the Type III secretion system in vitro and during infectionRole of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivoThe impact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis.Keeping their options open: acute versus persistent infectionsType III secretion-dependent modulation of innate immunity as one of multiple factors regulated by Pseudomonas aeruginosa RetS.Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cellsFactors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal.Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV.The importance of the Pseudomonas aeruginosa type III secretion system in epithelium traversal depends upon conditions of host susceptibilityExpression of Pseudomonas aeruginosa toxin ExoS effectively induces apoptosis in host cells.Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence.ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival.Human tear fluid protects against Pseudomonas aeruginosa keratitis in a murine experimental model.Traversal of multilayered corneal epithelia by cytotoxic Pseudomonas aeruginosa requires the phospholipase domain of exoU.The influence of human respiratory epithelia on Pseudomonas aeruginosa gene expression.TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways.Translocon-independent intracellular replication by Pseudomonas aeruginosa requires the ADP-ribosylation domain of ExoS.Why does the healthy cornea resist Pseudomonas aeruginosa infection?Host defense at the ocular surfaceAssociation between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitisPathogenic phenotype and genotype of Pseudomonas aeruginosa isolates from spontaneous canine ocular infections.Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates.Animal models of bacterial keratitis.Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity.Human Tear Fluid Reduces Culturability of Contact Lens-Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence-Associated Type III Secretion System.Innate immune regulation of Serratia marcescens-induced corneal inflammation and infectionGenetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections.Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis
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P2860
Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
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@yue
2003年學術文章
@zh-hant
name
Contribution of ExsA-regulated ...... a murine scarification model.
@en
Contribution of ExsA-regulated ...... a murine scarification model.
@nl
type
label
Contribution of ExsA-regulated ...... a murine scarification model.
@en
Contribution of ExsA-regulated ...... a murine scarification model.
@nl
prefLabel
Contribution of ExsA-regulated ...... a murine scarification model.
@en
Contribution of ExsA-regulated ...... a murine scarification model.
@nl
P356
P1476
Contribution of ExsA-regulated ...... n a murine scarification model
@en
P2093
Brigitte A Cowell
Ellen J Lee
P304
P356
10.1167/IOVS.02-1302
P407
P577
2003-09-01T00:00:00Z