Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.
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Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasisLeishCyc: a biochemical pathways database for Leishmania major.Phospholipid and sphingolipid metabolism in Leishmania.Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invasionLeishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern.Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens.Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania majorThe N-terminal domain and glycosomal localization of Leishmania initial acyltransferase LmDAT are important for lipophosphoglycan synthesisMetabolic variation during development in culture of Leishmania donovani promastigotes.Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategiesGlycoinositolphospholipids from Leishmania braziliensis and L. infantum: modulation of innate immune system and variations in carbohydrate structureThe role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania majorATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania majorLeishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment.Transbilayer dynamics of phospholipids in the plasma membrane of the Leishmania genusCharacterization of Leishmania major phosphatidylethanolamine methyltransferases LmjPEM1 and LmjPEM2 and their inhibition by choline analogsLeishmania lipophosphoglycan: how to establish structure-activity relationships for this highly complex and multifunctional glycoconjugate?Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum.Niche metabolism in parasitic protozoa.GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat.Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania.Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania majorLeishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesisRecent developments in the molecular, biochemical and functional characterization of GPI8 and the GPI-anchoring mechanism [review].The amastigote forms of Leishmania are experts at exploiting host cell processes to establish infection and persist.Attenuation of Leishmania infantum chagasi metacyclic promastigotes by sterol depletionDevelopmentally regulated sphingolipid synthesis in African trypanosomesPlasmenylethanolamine synthesis in Leishmania major.Transgenic Leishmania and the immune response to infectionLipidomic analysis of bloodstream and procyclic form Trypanosoma bruceiA novel phospholipase from Trypanosoma bruceiRegulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins.The LPG1 gene family of Leishmania major.Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis.Leishmania major phosphoglycans influence the host early immune response by modulating dendritic cell functionsLipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansSphingolipids are essential for differentiation but not growth in LeishmaniaLeishmania dihydroxyacetonephosphate acyltransferase LmDAT is important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes.The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host.Leishmania amazonensis exhibits phosphatidylserine-dependent procoagulant activity, a process that is counteracted by sandfly saliva.
P2860
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P2860
Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Ether phospholipids and glycos ...... ctivation by Leishmania major.
@en
Ether phospholipids and glycos ...... ctivation by Leishmania major.
@nl
type
label
Ether phospholipids and glycos ...... ctivation by Leishmania major.
@en
Ether phospholipids and glycos ...... ctivation by Leishmania major.
@nl
prefLabel
Ether phospholipids and glycos ...... ctivation by Leishmania major.
@en
Ether phospholipids and glycos ...... ctivation by Leishmania major.
@nl
P2093
P2860
P50
P921
P356
P1476
Ether phospholipids and glycos ...... activation by Leishmania major
@en
P2093
Deborah F Smith
Deborah R Sullivan
Igor C Almeida
Rachel Zufferey
Salvatore J Turco
Simon Allen
Tamara Barron
P2860
P304
44708-44718
P356
10.1074/JBC.M308063200
P407
P577
2003-08-27T00:00:00Z