Tyr-317 phosphorylation increases Shc structural rigidity and reduces coupling of domain motions remote from the phosphorylation site as revealed by molecular dynamics simulations.
about
Distinct signaling functions for Shc isoforms in the heartCell-signalling dynamics in time and space.Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.System properties of ErbB receptor signaling for the understanding of cancer progression.Molecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptorTeaching an old dogma new tricks: twenty years of Shc adaptor signalling.Novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and ErbB3 receptor-derived phosphotyrosyl peptides.An integrative top-down and bottom-up qualitative model construction framework for exploration of biochemical systems.
P2860
Q28572126-599897BB-915D-49F3-95CB-01E71EAC564AQ34495098-B97C8ACE-6252-4D82-B449-E6C002E409D7Q36559220-B2064734-9A61-4F1B-BBE3-631477ABDCF6Q36716462-6701A583-0C14-41EB-A046-D42323EC7BB9Q37279304-629F3E33-213D-4FFD-ACD8-01A81A376633Q38042699-7946CA6D-E62D-4276-B3EB-0E1C55BEB997Q40497408-CBB6DCDE-5464-4397-9FE3-F7EAF45F62F1Q40716239-FC98F806-8596-4F18-B04C-54E51B88C180
P2860
Tyr-317 phosphorylation increases Shc structural rigidity and reduces coupling of domain motions remote from the phosphorylation site as revealed by molecular dynamics simulations.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Tyr-317 phosphorylation increa ...... olecular dynamics simulations.
@en
Tyr-317 phosphorylation increa ...... olecular dynamics simulations.
@nl
type
label
Tyr-317 phosphorylation increa ...... olecular dynamics simulations.
@en
Tyr-317 phosphorylation increa ...... olecular dynamics simulations.
@nl
prefLabel
Tyr-317 phosphorylation increa ...... olecular dynamics simulations.
@en
Tyr-317 phosphorylation increa ...... olecular dynamics simulations.
@nl
P2093
P2860
P50
P356
P1476
Tyr-317 phosphorylation increa ...... molecular dynamics simulations
@en
P2093
Akihiko Konagaya
Atsushi Kawai
Atsushi Suenaga
Hideaki Furusawa
Kenji Yasuoka
Mariko Hatakeyama
Naoki Takada
Noriaki Okimoto
Noriyuki Futatsugi
Ryutaro Susukita
P2860
P304
P356
10.1074/JBC.M310598200
P407
P577
2003-11-12T00:00:00Z