Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism.
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Role for protease activity in visceral pain in irritable bowel syndromeNeuroimmunomodulation in the Gut: Focus on Inflammatory Bowel DiseaseRole of enteric neurotransmission in host defense and protection of the gastrointestinal tractContribution of bone marrow-derived cells to the pro-inflammatory effects of protease-activated receptor-2 in colitisA role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.Intestinal epithelial stem/progenitor cells are controlled by mucosal afferent nervesA major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis.Tryptase-PAR2 axis in experimental autoimmune prostatitis, a model for chronic pelvic pain syndromeSerine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants.Induction of apoptosis by thrombin in the cultured neurons of dorsal motor nucleus of the vagus.Role of protease activated receptor 2 in experimental acute lung injury and lung fibrosis.Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents.Modulation of visceral pain and inflammation by protease-activated receptors.Lesioning of TRPV1 expressing primary afferent neurons prevents PAR-2 induced motility, but not mechanical hypersensitivity in the rat colon.Gastrointestinal pain in functional bowel disorders: sensory neurons as novel drug targets.Clinical relevance of proteinase activated receptors (pars) in the gutProteinase-mediated cell signalling: targeting proteinase-activated receptors (PARs) by kallikreins and more.Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.Proteinase-activated receptor 2 (PAR-2) in gastrointestinal and pancreatic pathophysiology, inflammation and neoplasia.Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2.A role for proteinase-activated receptor-1 in inflammatory bowel diseasesEpidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells.Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice.Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.The C-terminus of murine S100A9 protein inhibits hyperalgesia induced by the agonist peptide of protease-activated receptor 2 (PAR2).Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs).Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice.Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins.PAR4: a new role in the modulation of visceral nociception.Colonic luminal proteases activate colonocyte proteinase-activated receptor-2 and regulate paracellular permeability in mice.PAR(2) and temporomandibular joint inflammation in the rat.PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways.Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.Experimental colitis modulates the functional properties of NMDA receptors in dorsal root ganglia neurons.Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine.
P2860
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P2860
Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@en
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@nl
type
label
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@en
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@nl
prefLabel
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@en
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@nl
P2093
P2860
P50
P356
P1476
Colitis induced by proteinase- ...... ted by a neurogenic mechanism.
@en
P2093
Anne-Marie Coelho
Cathy Nguyen
Eileen Grady
John L Wallace
Lionel Bueno
Martin Steinhoff
Morley D Hollenberg
Nigel W Bunnett
Steven J Compton
P2860
P304
P356
10.1139/Y03-080
P577
2003-09-01T00:00:00Z