Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice. - Wikidata - wikimedia - TriplyDB

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.

http://www.wikidata.org/entity/Q44680394

about

The mechanistic classification of addictive drugs Behavioral analyses of GHB: receptor mechanisms Baclofen and gamma-hydroxybutyrate withdrawal Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348)Unravelling the brain targets of gamma-hydroxybutyric acid Unmet needs of patients with narcolepsy: perspectives on emerging treatment options α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)γ-Hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptors Succinic semialdehyde dehydrogenase: biochemical-molecular-clinical disease mechanisms, redox regulation, and functional significance GABA(B) receptors, schizophrenia and sleep dysfunction: a review of the relationship and its potential clinical and therapeutic implications GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy.Hooked on benzodiazepines: GABAA receptor subtypes and addiction.Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.The use of sodium oxybate to treat narcolepsy.Specific roles of GABA(B(1)) receptor isoforms in cognition.Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice.A Novel Monocarboxylate Transporter Inhibitor as a Potential Treatment Strategy for γ-Hydroxybutyric Acid Overdose.GABAB receptor-positive modulators: brain region-dependent effects.GHB pharmacology and toxicology: acute intoxication, concentrations in blood and urine in forensic cases and treatment of the withdrawal syndrome.Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory.γ-Hydroxybutyrate (GHB)-induced respiratory depression: combined receptor-transporter inhibition therapy for treatment in GHB overdose.Extrasynaptic site of action for γ-hydroxybutyrate.Cataleptic effects of gamma-hydroxybutyrate (GHB) and baclofen in mice: mediation by GABA(B) receptors, but differential enhancement by N-methyl-d-aspartate (NMDA) receptor antagonists.Effects of gamma hydroxybutyric acid on inhibition and excitation in rat neocortex Gamma-hydroxybutyrate--a drug of abuse.The critical role of sleep spindles in hippocampal-dependent memory: a pharmacology study.Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma-hydroxybutyrate associated with its deficiency Allosteric modulators of GABA(B) receptors: mechanism of action and therapeutic perspective.Toxicokinetics/Toxicodynamics of γ-hydroxybutyrate-ethanol intoxication: evaluation of potential treatment strategies.Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.Reconsidering GHB: orphan drug or new model antidepressant?A critical evaluation of the gamma-hydroxybutyrate (GHB) model of absence seizures.A single acute pharmacological dose of γ-hydroxybutyrate modifies multiple gene expression patterns in rat hippocampus and frontal cortex.Challenges in the development of therapeutics for narcolepsy.Mechanisms for the Specific Properties of γ-Hydroxybutyrate in Brain.The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.Activation of astroglial calcium signaling by endogenous metabolites succinate and gamma-hydroxybutyrate in the nucleus accumbens.Subcellular distribution of GABA(B) receptor homo- and hetero-dimers.

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P2860

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.

http://www.wikidata.org/entity/Q44680394

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

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2003年學術文章

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2003年學術文章

@zh-hant

name

Specific gamma-hydroxybutyrate ...... gamma-hydroxybutyrate in GABA

@nl

Specific gamma-hydroxybutyrate ...... in GABA(B)(1)-deficient mice.

@en

type

label

Specific gamma-hydroxybutyrate ...... gamma-hydroxybutyrate in GABA

@nl

Specific gamma-hydroxybutyrate ...... in GABA(B)(1)-deficient mice.

@en

prefLabel

Specific gamma-hydroxybutyrate ...... gamma-hydroxybutyrate in GABA

@nl

Specific gamma-hydroxybutyrate ...... in GABA(B)(1)-deficient mice.

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J.1460-9568.2003.03013.X

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European Journal of Neuroscience

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Specific gamma-hydroxybutyrate ...... in GABA(B)(1)-deficient mice.

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Bernhard Bettler

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Cedric Mombereau

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Gilles Sansig

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Herman van der Putten

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Johannes Mosbacher

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Klaus Klebs

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Klemens Kaupmann

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Markus Schmutz

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Peter Waldmeier

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Wolfgang Froestl

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2722-2730

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scholarly article

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10.1111/J.1460-9568.2003.03013.X

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10

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Petrine Wellendorph

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2003-11-01T00:00:00Z

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8976224

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