Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.
about
Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complexPeroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cellsVEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinasePGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseEstrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscleMitochondria in the diabetic heartPGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosisMitochondrial Mechanisms in Septic CardiomyopathyMitochondrial dynamism and heart disease: changing shape and shaping changeRedox regulation of mitochondrial biogenesisMaternal cardiac metabolism in pregnancyNew insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyondTranscriptional integration of mitochondrial biogenesisMitochondria as a therapeutic target in heart failurePGC-1 proteins and heart failureHypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolismPGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performanceMitochondrial Metabolism in Aging HeartCardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.Cardiac involvement in mitochondrial DNA disease: clinical spectrum, diagnosis, and management.PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure.MEF2C silencing attenuates load-induced left ventricular hypertrophy by modulating mTOR/S6K pathway in miceAssociation and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic functionEndothelial PGC-1α mediates vascular dysfunction in diabetes.Abcc9 is required for the transition to oxidative metabolism in the newborn heart.The role of PGC-1 coactivators in aging skeletal muscle and heart.Defective DNA replication impairs mitochondrial biogenesis in human failing heartsPGC-1α and exercise in the control of body weight.A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsisGenome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1.Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factorsUbiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathwayPGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolismCardiac-specific inhibition of kinase activity in calcium/calmodulin-dependent protein kinase kinase-β leads to accelerated left ventricular remodeling and heart failure after transverse aortic constriction in mice.Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulationPromoting PGC-1α-driven mitochondrial biogenesis is detrimental in pressure-overloaded mouse hearts.
P2860
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P2860
Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Cardiac-specific induction of ...... mental stage-dependent manner.
@en
Cardiac-specific induction of ...... mental stage-dependent manner.
@nl
type
label
Cardiac-specific induction of ...... mental stage-dependent manner.
@en
Cardiac-specific induction of ...... mental stage-dependent manner.
@nl
prefLabel
Cardiac-specific induction of ...... mental stage-dependent manner.
@en
Cardiac-specific induction of ...... mental stage-dependent manner.
@nl
P2093
P1433
P1476
Cardiac-specific induction of ...... mental stage-dependent manner.
@en
P2093
Attila Kovacs
Carolyn M Mansfield
Daniel P Kelly
Denis M Medeiros
Jeffrey E Saffitz
John J Lehman
Laurie K Russell
Michael Courtois
P304
P356
10.1161/01.RES.0000117088.36577.EB
P577
2004-01-15T00:00:00Z