Identification of species-specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1.
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Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonistsHuman embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegenerationTRP channels in schistosomesEvidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoniTRPV1 structures in distinct conformations reveal activation mechanismsThe cold and menthol receptor TRPM8 contains a functionally important double cysteine motifTRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid actionTRPV1 ligands with hyperthermic, hypothermic and no temperature effects in ratsTRPV1 and TRPV4 play pivotal roles in delayed onset muscle soreness.Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migrationA bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domainRole of TRPV1 in the Differentiation of Mouse Embryonic Stem Cells into Cardiomyocytes.Structural insight into tetrameric hTRPV1 from homology modeling, molecular docking, molecular dynamics simulation, virtual screening, and bioassay validations.High-resolution views of TRPV1 and their implications for the TRP channel superfamily.Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegenerationA structural view of ligand-dependent activation in thermoTRP channels.Structure-Driven Pharmacology of Transient Receptor Potential Channel Vanilloid 1.Expression and functionality of TRPV1 receptor in human MCF-7 and canine CF.41 cells.Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels.Targeting the transient receptor potential vanilloid type 1 (TRPV1) assembly domain attenuates inflammation-induced hypersensitivity.Novel gating and sensitizing mechanism of capsaicin receptor (TRPV1): tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV1.Distinct modulations of human capsaicin receptor by protons and magnesium through different domains.Functional characterisation of the S512Y mutant vanilloid human TRPV1 receptor.Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore.Activation of transient receptor potential melastatin 8 reduces ultraviolet B-induced prostaglandin E2 production in keratinocytes.Capsazepine concentration dependently inhibits currents in HEK 293 cells mediated by human hyperpolarization-activated cyclic nucleotide-gated 2 and 4 channels.A residue in the TRPM2 channel outer pore is crucial in determining species-dependent sensitivity to extracellular acidic pH
P2860
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P2860
Identification of species-specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-hans
2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@en
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@nl
type
label
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@en
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@nl
prefLabel
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@en
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@nl
P2860
P356
P1476
Identification of species-spec ...... nd the agonist PPAHV on TRPV1.
@en
P2093
Alison Reeve
Elsa Phillips
P2860
P304
17165-17172
P356
10.1074/JBC.M313328200
P407
P577
2004-02-11T00:00:00Z