about
Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.Pharmacokinetic and pharmacodynamic modeling of pegylated thrombopoietin mimetic peptide (PEG-TPOm) after single intravenous dose administration in healthy subjects.JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.Expression of protein kinase CI in NIH 3T3 cells increases its growth response to specific activators.Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors.Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitors.Epidermal growth factor activates phosphoinositide turnover and protein kinase C in BALB/MK keratinocytes.Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors.Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors.Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s.A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s.Effect of retinoid deficiency on keratin expression in mouse bladderEndothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for common signaling mechanismsEffects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptorsActivin A and TGF-beta stimulate phosphorylation of focal adhesion proteins and cytoskeletal reorganization in rat aortic smooth muscle cellsDiscovery of novel FMS kinase inhibitors as anti-inflammatory agentsStructure-based optimization of a potent class of arylamide FMS inhibitorsA functional radioreceptor assay of alpha-V-beta-3 (alphavbeta3) inhibitors in plasma: application as an ex vivo pharmacodynamic modelThe discovery of novel cyclohexylamide CCR2 antagonistsReducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitorsDesign and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s
P50
Q33211997-764E0055-4EA6-4084-8241-34AC768AC924Q33383425-95A798A5-EC1C-4B06-B344-7D9AE8A758E8Q33383483-766DBD55-A191-48DC-9A09-D542B524F276Q39779519-B1689AF9-05B4-4515-B2C5-6CFF29168B4FQ41747283-E4C8C9AE-8E54-4FF3-BDB7-3CE4562A7E45Q43569166-8DA45D5D-2EFA-48AC-82F3-1141B831BB67Q43621522-8D84A550-9992-4CC6-8BC0-9FD1BA2241A1Q44031746-FD274428-7090-4015-AA35-12A3A00D8DD7Q44787884-0C73895E-4A52-4383-AC67-73773A2BA91FQ46727271-0CAADD4B-0ACA-426D-BBED-96EF8021E091Q46741638-E97CBE73-E7F1-44AB-83A9-547E2FA1CF5EQ46776589-99440E79-7279-4C7D-8C44-3AC36DBF8C65Q46930168-B91DCA9A-24AA-4A9A-873F-5D45A7944893Q69033118-7470597D-4010-4C59-9874-819D293485EAQ72391492-9529FB23-9384-4010-86DE-59198D1B7007Q72968498-F0424060-7EFA-43B6-AAFB-DCDAD5B30067Q78101958-7F9D6EC2-3377-4707-AB35-769FA62E2C9AQ80614536-34A0A517-88D8-485D-B21A-EF587E770520Q81317997-9030F44B-0A80-4A8C-A3E4-4EAB1D191CC2Q81570258-242837B5-6E17-470B-AC4A-3626327FF47BQ82397337-79FE0EFB-D530-4189-BBCA-D97794787FEEQ84459598-987F7C2C-3C9F-4BAE-AD58-0486B5BF1580Q84573273-773D9FB1-05D9-410B-96FE-1F903BEDA997
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Christopher J. Molloy
@ast
Christopher J. Molloy
@en
Christopher J. Molloy
@es
Christopher J. Molloy
@nl
Christopher J. Molloy
@sl
type
label
Christopher J. Molloy
@ast
Christopher J. Molloy
@en
Christopher J. Molloy
@es
Christopher J. Molloy
@nl
Christopher J. Molloy
@sl
altLabel
CJ Molloy
@en
Chris Molloy
@en
Christopher John Molloy
@en
Christopher Molloy
@en
prefLabel
Christopher J. Molloy
@ast
Christopher J. Molloy
@en
Christopher J. Molloy
@es
Christopher J. Molloy
@nl
Christopher J. Molloy
@sl
P1053
A-6821-2013
P106
P1153
7006761761
P21
P31
P3829
P496
0000-0003-2964-6166