Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome.
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Control of autoimmune CNS inflammation by astrocytesA combined CXCL10, CXCL8 and H-FABP panel for the staging of human African trypanosomiasis patientsIFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain InjuryChronic CXCL10 alters neuronal properties in rat hippocampal culture.Neuroinflammation in delirium: a postmortem case-control study.MicroRNA-146a: a key regulator of astrocyte-mediated inflammatory response.IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunityCase definition and classification of leukodystrophies and leukoencephalopathies.Tissue-specific interferon alpha subtype response to SIV infection in brain, spleen, and lung.Immunoinflammatory diseases of the central nervous system - the tale of two cytokines.Elevation of proinflammatory cytokines in patients with Aicardi-Goutières syndromeRibonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.Potent induction of IFN-alpha and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus.Aicardi-Goutières syndrome: clues from the RNase H2 knock-out mouse.Immune players in the CNS: the astrocyte.Interferons in the central nervous system: a few instruments play many tunes.Human disease phenotypes associated with mutations in TREX1.Type I interferon dysregulation and neurological disease.Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms.Interferon-α and the calcifying microangiopathy in Aicardi-Goutières syndrome.Canonical type I IFN signaling in simian immunodeficiency virus-infected macrophages is disrupted by astrocyte-secreted CCL2.Theiler's virus infection provokes the overexpression of genes coding for the chemokine Ip10 (CXCL10) in SJL/J murine astrocytes, which can be inhibited by modulators of estrogen receptors.Simian immunodeficiency virus infection in the brain and lung leads to differential type I IFN signaling during acute infection.A broad upregulation of cerebral chemokine genes by peripherally-generated inflammatory mediators.Different mutations in three prime repair exonuclease 1 and ribonuclease H2 genes affect clinical features in Aicardi-Goutieres syndrome.An in vitro experimental model of neuroinflammation: the induction of interleukin-6 in murine astrocytes infected with Theiler's murine encephalomyelitis virus, and its inhibition by oestrogenic receptor modulators.Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.Aicardi-Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies.Discrimination of agonist and antagonist forms of CXCL10 in biological samples.Advances in Biomarker-Guided Therapy for Pediatric- and Adult-Onset Neuroinflammatory Disorders: Targeting Chemokines/Cytokines.RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation.
P2860
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P2860
Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
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2008年學術文章
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name
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@en
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@nl
type
label
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@en
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@nl
prefLabel
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@en
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@nl
P2093
P2860
P356
P1433
P1476
Astrocytes produce interferon- ...... in Aicardi-Goutières syndrome.
@en
P2093
Dirk Troost
Flore Rozenberg
Jane T van Heteren
Pierre Lebon
P2860
P304
P356
10.1002/GLIA.20639
P577
2008-04-01T00:00:00Z