Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
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ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversalInteraction of Isoflavones with the BCRP/ABCG2 Drug TransporterTransporters at CNS barrier sites: obstacles or opportunities for drug delivery?Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives?A novel two mode-acting inhibitor of ABCG2-mediated multidrug transport and resistance in cancer chemotherapyPhytochemistry and pharmacology of Ferula persica Boiss.: A reviewDeterminants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).A high-throughput cell-based assay for inhibitors of ABCG2 activity.New inhibitors of ABCG2 identified by high-throughput screeningIsoflavones are safe compounds for therapeutical applications - evaluation of in vitro data.Identification and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3).Regulation of gene expression in brain tissues of rats repeatedly treated by the highly abused opioid agonist, oxycodone: microarray profiling and gene mapping analysis.Polyphenolic extract of InsP 5-ptase expressing tomato plants reduce the proliferation of MCF-7 breast cancer cells.Isoflavones, their Glycosides and Glycoconjugates. Synthesis and Biological Activity.Oral epithelial stem cells - implications in normal development and cancer metastasis.Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).Mutual interactions between flavonoids and enzymatic and transporter elements responsible for flavonoid disposition via phase II metabolic pathways.Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport--an update.The challenge of exploiting ABCG2 in the clinic.A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells.Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.The in vitro cytotoxic activity of ethno-pharmacological important plants of Darjeeling district of West Bengal against different human cancer cell lines.A physiologically based pharmacokinetic model of mitoxantrone in mice and scale-up to humans: a semi-mechanistic model incorporating DNA and protein binding.Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy.The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).BCRP Inhibition: from Data Collection to Ligand-Based Modeling.Role of the breast cancer resistance protein (ABCG2) in drug transport.Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.Current industrial practices of assessing permeability and P-glycoprotein interactionBreast cancer resistance protein in pharmacokinetics and drug-drug interactions.Human ABC transporter ABCG2 in xenobiotic protection and redox biology.Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance.BCRP/ABCG2 in the placenta: expression, function and regulation.Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein TransporterEscape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2.Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo)Disposition of flavonoids via enteric recycling: determination of the UDP-glucuronosyltransferase isoforms responsible for the metabolism of flavonoids in intact Caco-2 TC7 cells using siRNA.Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Quantum-SAR extension of the spectral-SAR algorithm: application to polyphenolic anticancer bioactivityMicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells.
P2860
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P2860
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
@en
Flavonoids are inhibitors of breast cancer resistance protein
@nl
type
label
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
@en
Flavonoids are inhibitors of breast cancer resistance protein
@nl
prefLabel
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
@en
Flavonoids are inhibitors of breast cancer resistance protein
@nl
P2093
P356
P1476
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
@en
P2093
Marilyn E Morris
Shuzhong Zhang
Xinning Yang
P304
P356
10.1124/MOL.65.5.1208
P577
2004-05-01T00:00:00Z