Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
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Evidence for natural antisense transcript-mediated inhibition of microRNA functionBiological markers of amyloid beta-related mechanisms in Alzheimer's diseaseExpression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretaseAmyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresPlatelets and Alzheimer's disease: Potential of APP as a biomarkerCerebrospinal fluid and blood biomarkers in Alzheimer's diseaseBACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous systemModulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's diseaseModulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's diseaseΒ-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis.A common BACE1 polymorphism is a risk factor for sporadic Creutzfeldt-Jakob diseaseCerebrospinal Aβ11-x and 17-x levels as indicators of mild cognitive impairment and patients' stratification in Alzheimer's disease.CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease.Loss of Bace1 in mice does not alter the severity of caerulein induced pancreatitis.Cerebrospinal Fluid P-Tau181P: Biomarker for Improved Differential Dementia Diagnosis.BACE1 as a potential biomarker for Alzheimer's diseaseMitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.Fluid biomarkers in Alzheimer disease.Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease.Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer's diseaseAlzheimer disease and platelets: how's that relevant.Fluid biomarkers in Alzheimer's disease - current conceptsUpdate on amyloid-beta homeostasis markers for sporadic Alzheimer's disease.CSF Presenilin-1 complexes are increased in Alzheimer's diseaseBACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer's Disease Markers in Elderly Healthy Participants.Is BACE1 a suitable therapeutic target for the treatment of Alzheimer's disease? Current strategies and future directions.Cerebrospinal fluid biomarkers for Alzheimer's disease: the present and the future.Role of CSF biomarkers in the diagnosis of prodromal Alzheimer's disease.Splice variants of the Alzheimer's disease beta-secretase, BACE1.BACE1 as a therapeutic target in Alzheimer's disease: rationale and current status.Biomarker modelling of early molecular changes in Alzheimer's disease.Transmembrane Amyloid-Related Proteins in CSF as Potential Biomarkers for Alzheimer's Disease.Biomarkers in Sporadic and Familial Alzheimer's Disease.The Antisense Transcriptome and the Human Brain.APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding.Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer's Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer's Disease Neuroimaging Initiative-1 Baseline Cohort.Cerebrospinal fluid profiles of amyloid β-related biomarkers in Alzheimer's disease.Alpha- and gamma-synuclein proteins are present in cerebrospinal fluid and are increased in aged subjects with neurodegenerative and vascular changes.Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.Characterization of plasma β-secretase (BACE1) activity and soluble amyloid precursor proteins as potential biomarkers for Alzheimer's disease.
P2860
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P2860
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
@en
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
@nl
type
label
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
@en
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
@nl
prefLabel
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
@en
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
@nl
P2093
P356
P1433
P1476
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects
@en
P2093
Colin L Masters
Geneviève Evin
Steven J Collins
P304
P356
10.1002/ANA.20144
P577
2004-06-01T00:00:00Z