Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase. - Wikidata - wikimedia - TriplyDB

Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase.

Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase.

http://www.wikidata.org/entity/Q45016660

about

Why do HIV-1 and HIV-2 use different pathways to develop AZT resistance?Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template Recent findings on the mechanisms involved in tenofovir resistance.Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) inhibits HIV-1 reverse transcriptase with multiple mechanisms Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir Understanding the molecular mechanism of sequence dependent tenofovir removal by HIV-1 reverse transcriptase: differences in primer binding site versus polypurine tract NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase.Mechanism by which a glutamine to leucine substitution at residue 509 in the ribonuclease H domain of HIV-1 reverse transcriptase confers zidovudine resistance.Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.A new general method for simultaneous fitting of temperature and concentration dependence of reaction rates yields kinetic and thermodynamic parameters for HIV reverse transcriptase specificity.Chain-terminating dinucleoside tetraphosphates are substrates for DNA polymerization by human immunodeficiency virus type 1 reverse transcriptase with increased activity against thymidine analogue-resistant mutants.Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure.Evaluation of Sofosbuvir (β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine) as an inhibitor of Dengue virus replication.Resolution of Specific Nucleotide Mismatches by Wild-Type and AZT-Resistant Reverse Transcriptases during HIV-1 Replication.Biochemical studies on the mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to 1-(beta-D-dioxolane)thymine triphosphate.A role of template cleavage in reduced excision of chain-terminating nucleotides by human immunodeficiency virus type 1 reverse transcriptase containing the M184V mutation.

P2860

Q25256872-6EE8257A-2D6C-4002-9DA1-6835CC1A8C87 Q33381540-8D5352FC-0E46-4B09-866B-D6A10FFECA75 Q33831709-343F7A43-3801-49F0-A89F-335D29068FB1 Q33836938-FC15F22A-E9ED-476C-B481-77506BFC6E09 Q33896402-7E1B5087-E42D-4988-91C2-D3D0B79F17B1 Q34107343-3D1BB6B0-A079-4E7C-84C4-F4DA236A1A54 Q35912746-B29FC2D2-6ACE-4DBA-83E7-ED943CDBF463 Q36098779-0E5E3746-2672-43A1-A219-277BDB95798C Q36583173-B1019519-12C0-47BB-80D3-A356680613D5 Q37338779-DE90DC48-3A66-4E86-A561-7870A1FD8D7F Q37372064-664BFEB2-2650-4586-B1AD-8B9BB24B763F Q38932237-7BCFEFF9-1C81-4820-9545-C9068D5B4E6E Q39077432-B4482541-7C59-4AD8-84FD-A8CC9583CD2A Q39664167-AA41A930-728F-4481-8258-34FB9E572A86 Q40046618-0E69F2F9-D681-4D79-9425-F6566BADB70E Q40802197-6F860D0A-FD8C-49AD-B789-5B4ACB9A000D Q41856023-056EB02D-2206-4240-BF4F-25142960E5F4 Q41862836-7B5A6080-5A73-4C78-B41F-02ECDCF60C88

P2860

Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase.

http://www.wikidata.org/entity/Q45016660

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年学术文章

@wuu

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh

2004年學術文章

@zh-hant

name

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@en

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@nl

type

label

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@en

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@nl

prefLabel

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@en

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@nl

P1433

Q45016660-35EDE87C-F9A3-4B0C-894F-9C808179C72A

P1476

Q45016660-49D61CD3-95FE-4A7A-B033-70DC78036E9B

P2093

Q45016660-579DBEB4-1D97-4DC7-BD43-2CC24B983032

Q45016660-7AEBCBE1-B3E9-4F89-A542-055224939893

Q45016660-8C573C45-DAF1-4AF1-8ABC-D8E166EDBDD9

Q45016660-EF188C3B-ACA9-4A9F-8165-E2B4436885AF

P2860

Q45016660-06D6D7A8-CFA8-4058-B788-1DD67399B50F

Q45016660-09FBDFEA-8DD1-4178-8EE5-1AD883CCD96A

Q45016660-16D68795-80E3-4F17-A11E-8A0661E2CB69

Q45016660-36D7BC70-82C9-4452-853D-BFB95C2ADAA1

Q45016660-394AB0D9-D74A-40C8-AE16-DAFB37079658

Q45016660-3F5BFF20-F292-4689-AC6C-B42E4B494472

Q45016660-3FE36D66-3239-468A-9FBC-C2FE196D0DDE

Q45016660-43DF045E-323C-43E6-AD7F-7463103C918E

Q45016660-454D6620-9B44-4911-AA41-71773BB202A4

Q45016660-512BFF02-A451-4741-859F-C8733E4B1EC0

P304

Q45016660-794DE8D7-AB31-431F-A96F-2AB84D2D1D82

P31

Q45016660-1EDF3576-97EA-4B1B-A310-7EAEE133758B

P356

Q45016660-E3C3A09A-8C51-4767-AF86-B3195060AA81

P407

Q45016660-965D0219-C457-4492-BF7E-31EE4C2825DE

P433

Q45016660-D530CB13-AEFA-4443-9DB8-4F55A0B4C8FE

P478

Q45016660-99052392-25C6-49FC-9466-02C9581C119C

P577

Q45016660-5A040825-FE78-401E-A5EF-773CA1B33C52

P698

Q45016660-7D54A225-D04F-4D5D-8079-6C39E2A70B67

P356

P1433

Journal of Biological Chemistry

P1476

Effects of primer-template seq ...... y HIV-1 reverse transcriptase.

@en

P2093

Anthony J Smith

http://www.w3.org/2001/XMLSchema#string

Peter R Meyer

http://www.w3.org/2001/XMLSchema#string

Suzanne E Matsuura

http://www.w3.org/2001/XMLSchema#string

Walter A Scott

http://www.w3.org/2001/XMLSchema#string

P2860

Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase

Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.

Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

Functional characterization of RNA-dependent DNA polymerase and RNase H activities of a recombinant HIV reverse transcriptase

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture.

The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1

Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.

P304

45389-45398

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M405072200

http://www.w3.org/2001/XMLSchema#string

P407

P433

44

http://www.w3.org/2001/XMLSchema#string

P478

279

http://www.w3.org/2001/XMLSchema#string

P577

2004-08-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15308646

http://www.w3.org/2001/XMLSchema#string