CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.
about
Siglecs as sensors of self in innate and adaptive immune responsesSiglecs and immune regulationCD22 and Siglec-G in B cell function and toleranceRethinking mechanisms of autoimmune pathogenesisComparative Transcriptomic Analysis of Rectal Tissue from Beef Steers Revealed Reduced Host Immunity in Escherichia coli O157:H7 Super-SheddersCD22: an inhibitory enigmaRegulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic beta cellsB cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esteraseAmplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice.Augmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse lineDecoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivoAlpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics.B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.Loss of Siglec expression on T lymphocytes during human evolution.Differential roles of estrogen receptors α and β in control of B-cell maturation and selection.ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signalingB lymphocytes: how they develop and function.Characterizing the glycome of the mammalian immune system.Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.The Bs20x22 anti-CD20-CD22 bispecific antibody has more lymphomacidal activity than do the parent antibodies alone.Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice.Altered granulopoietic profile and exaggerated acute neutrophilic inflammation in mice with targeted deficiency in the sialyltransferase ST6Gal IGerminal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation.Vitamin D binding protein isoforms as candidate predictors of disease extension in childhood arthritis.Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.Epratuzumab (humanised anti-CD22 antibody) in autoimmune diseases.Sialic acids and autoimmune disease.Cis interactions of immunoreceptors with MHC and non-MHC ligands.Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesisCD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals.Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice.CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactionsRegulation of B-cell entry into the cell cycleDendritic cell-dependent inhibition of B cell proliferation requires CD22Basic and clinical immunology of SiglecsA reevaluation of CD22 expression in human lung cancer.Physiological Exploration of the Long Term Evolutionary Selection against Expression of N-Glycolylneuraminic Acid in the Brain.Structural basis for recognition of cellular and viral ligands by NK cell receptors.
P2860
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P2860
CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@en
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@nl
type
label
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@en
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@nl
prefLabel
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@en
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@nl
P2093
P2860
P356
P1433
P1476
CD22 regulates B lymphocyte fu ...... ligand-independent mechanisms.
@en
P2093
Ann S Miller
Cheryl B Bock
Isaac G Sanford
Jonathan C Poe
Karen M Haas
Manabu Fujimoto
Minoru Hasegawa
Thomas F Tedder
Yoko Fujimoto
P2860
P304
P356
10.1038/NI1121
P407
P577
2004-09-19T00:00:00Z