Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.
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Silencing or knocking out the Na(+)/Ca(2+) exchanger-3 (NCX3) impairs oligodendrocyte differentiation.Ionic homeostasis in brain conditioningCa2+ regulation of ion transport in the Na+/Ca2+ exchangerNon-Coding RNAs in Stroke and NeuroprotectionHypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitroProteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemiaMicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits.Palmitoylation of the Na/Ca exchanger cytoplasmic loop controls its inactivation and internalization during stress signalingDisruption of ionic and cell volume homeostasis in cerebral ischemia: The perfect stormProbing the role of the sodium/calcium exchanger in pentylenetetrazole-induced generalized seizures in rats.ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia.The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia.Electrophysiological characterization of the archaeal transporter NCX_Mj using solid supported membrane technology.Molecular physiology of preconditioning-induced brain tolerance to ischemia.Post-ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy.Neuroprotection by GDNF in the ischemic brain.Ionic transporter activity in astrocytes, microglia, and oligodendrocytes during brain ischemiaDoes Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention?The role of Na+/Ca2+ exchanger subtypes in neuronal ischemic injury.Novel Cellular Mechanisms for Neuroprotection in Ischemic Preconditioning: A View from Inside Organelles.Endoplasmic reticulum stress in brain ischemia.Glial Na(+) -dependent ion transporters in pathophysiological conditions.A new cell-penetrating peptide that blocks the autoinhibitory XIP domain of NCX1 and enhances antiporter activity.Genetics of ion homeostasis in Ménière's Disease.Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines.Amiloride Analogs as ASIC1a Inhibitors.Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via AktThe NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype.Transgenic overexpression of adenosine kinase aggravates cell death in ischemia.ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells.Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange.Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions.A concerted role of Na+ -K+ -Cl- cotransporter and Na+/Ca2+ exchanger in ischemic damage.Reverse NCX Attenuates Cellular Sodium Loading in Metabolically Compromised Cortex.Involvement of the potassium-dependent sodium/calcium exchanger gene product NCKX2 in the brain insult induced by permanent focal cerebral ischemia.Glutamate as a potential "survival factor" in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na+/Ca2+ exchanger.NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson's Disease.
P2860
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P2860
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-hans
2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Two sodium/calcium exchanger g ...... anent focal cerebral ischemia.
@en
Two sodium/calcium exchanger g ...... anent focal cerebral ischemia.
@nl
type
label
Two sodium/calcium exchanger g ...... anent focal cerebral ischemia.
@en
Two sodium/calcium exchanger g ...... anent focal cerebral ischemia.
@nl
prefLabel
Two sodium/calcium exchanger g ...... anent focal cerebral ischemia.
@en
Two sodium/calcium exchanger g ...... anent focal cerebral ischemia.
@nl
P2093
P50
P1433
P1476
Two sodium/calcium exchanger g ...... manent focal cerebral ischemia
@en
P2093
Adriana Canitano
Anna Tortiglione
Gianfranco Di Renzo
Pasqualina Castaldo
Rosaria Gala
Rossana Sirabella
Salvatore Amoroso
P304
P356
10.1161/01.STR.0000143730.29964.93
P407
P577
2004-10-07T00:00:00Z