A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
about
NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingThe stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γThe glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7Inhibition of c-Myc activity by ribosomal protein L11MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradationIsoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligaseSCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysisMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationInsights into the key roles of proteoglycans in breast cancer biology and translational medicineDysregulation of ubiquitin ligases in cancerA Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteinsMultiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signalingThe 19 S proteasomal subunit POH1 contributes to the regulation of c-Jun ubiquitination, stability, and subcellular localizationWogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradationDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway.The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.Inference of cell cycle-dependent proteolysis by laser scanning cytometry.Aberrant regulation of FBW7 in cancer.A positive feedback loop between EBP2 and c-Myc regulates rDNA transcription, cell proliferation, and tumorigenesisMYC Deregulation in Primary Human Cancers.Ras activity regulates cyclin E degradation by the Fbw7 pathway.The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancerMYC cofactors: molecular switches controlling diverse biological outcomes.SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stabilityThe emerging role of the COP9 signalosome in cancer.Multilayer control of the EMT master regulators.Ubiquitin-dependent proteolysis in G1/S phase control and its relationship with tumor susceptibilityMerkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7.Cullins and cancer.Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye.Multiple novel alternative splicing forms of FBXW7α have a translational modulatory function and show specific alteration in human cancer.Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.CSN6 drives carcinogenesis by positively regulating Myc stability.Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells
P2860
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P2860
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@en
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@nl
type
label
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@en
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@nl
prefLabel
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@en
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@nl
P2093
P1433
P1476
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
@en
P2093
Amir Orian
Bruce E Clurman
Jonathan E Grim
Robert N Eisenman
P304
P356
10.1016/J.CUB.2004.09.083
P407
P577
2004-10-01T00:00:00Z