Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils.
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Force per cross-sectional area from molecules to muscles: a general property of biological motors.Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy PhenotypeWhy Is there a Limit to the Changes in Myofilament Ca2+-Sensitivity Associated with Myopathy Causing Mutations?Cardiac thin filament regulationCa(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filDeletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kineticsDisease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates.Effects of HCM cTnI mutation R145G on troponin structure and modulation by PKA phosphorylation elucidated by molecular dynamics simulationsEngineered troponin C constructs correct disease-related cardiac myofilament calcium sensitivity.Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation.Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic miceStructural and functional consequences of cardiac troponin C L57Q and I61Q Ca(2+)-desensitizing variantsMechanical and energetic properties of papillary muscle from ACTC E99K transgenic mouse models of hypertrophic cardiomyopathy.The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation.Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation.Differences between cardiac and skeletal troponin interaction with the thin filament probed by troponin exchange in skeletal myofibrilsIncreased myofilament Ca2+-sensitivity and arrhythmia susceptibility.Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility.Order-Disorder Transitions in the Cardiac Troponin Complex.Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I.Restrictive Cardiomyopathy Troponin I R145W Mutation Does Not Perturb Myofilament Length-dependent Activation in Human Cardiac Sarcomeres.Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils.Myocardial contractile and metabolic properties of familial hypertrophic cardiomyopathy caused by cardiac troponin I gene mutations: a simulation study.Thin-filament regulation of force redevelopment kinetics in rabbit skeletal muscle fibres.
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P2860
Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils.
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2005 nî lūn-bûn
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2005年の論文
@ja
2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
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2005年學術文章
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name
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@en
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@nl
type
label
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@en
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@nl
prefLabel
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@en
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@nl
P2093
P2860
P1476
Effects of the mutation R145G ...... n isolated cardiac myofibrils.
@en
P2093
N Blaudeck
S Zittrich
P2860
P304
P356
10.1113/JPHYSIOL.2004.079095
P407
P577
2005-02-17T00:00:00Z