P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts. - Wikidata - wikimedia - TriplyDB

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

http://www.wikidata.org/entity/Q45275681

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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy Expression analysis of G Protein-Coupled Receptors in mouse macrophages Cell Death in Chondrocytes, Osteoblasts, and Osteocytes Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival.Development of selective agonists and antagonists of P2Y receptors.Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation.Reduced bone turnover in mice lacking the P2Y13 receptor of ADP.Modeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage.Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells.P2Y nucleotide receptors: promise of therapeutic applications Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts Purinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblasts Selective induction of endothelial P2Y6 nucleotide receptor promotes vascular inflammation.P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.AMP-activated protein kinase as regulator of P2Y(6) receptor-induced insulin secretion in mouse pancreatic β-cells Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.Thymidine 5'-O-monophosphorothioate induces HeLa cell migration by activation of the P2Y6 receptor.Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes.P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells.P2 purinergic receptor modulation of cytokine production.Rolofylline, an adenosine A1 receptor antagonist, inhibits osteoclast differentiation as an inverse agonist.Selective induction of P2Y14 receptor by RANKL promotes osteoclast formation.Purinergic signalling in the musculoskeletal system.Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury.Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis.P2X and P2Y nucleotide receptors as targets in cardiovascular disease.Mesenchymal Stem Cells Ageing: Targeting the "Purinome" to Promote Osteogenic Differentiation and Bone Repair.Osteopontin signals through calcium and nuclear factor of activated T cells (NFAT) in osteoclasts: a novel RGD-dependent pathway promoting cell survival Nuclear translocation of NF-κB in intact human gut tissue upon stimulation with coffee and roasting products.Activation of transcription factors by extracellular nucleotides in immune and related cell types.P2Y6 Receptor Antagonist MRS2578 Inhibits Neutrophil Activation and Aggregated Neutrophil Extracellular Trap Formation Induced by Gout-Associated Monosodium Urate Crystals.The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction.The P2X7 Receptor is an Important Regulator of Extracellular ATP Levels.Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks 15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts.Role of ecto-NTPDases on UDP-sensitive P2Y(6) receptor activation during osteogenic differentiation of primary bone marrow stromal cells from postmenopausal women.Functional coupling expression of COX-2 and cPLA2 induced by ATP in rat vascular smooth muscle cells: role of ERK1/2, p38 MAPK, and NF-kappaB.

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P2860

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

http://www.wikidata.org/entity/Q45275681

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@en

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@nl

type

label

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@en

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@nl

prefLabel

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@en

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@nl

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Journal of Biological Chemistry

P1476

P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.

@en

P2093

Jasminka Korcok

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Lin N Raimundo

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S Jeffrey Dixon

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Stephen M Sims

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Xiaobing Du

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P2860

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

Cloning, functional expression and tissue distribution of the human P2Y6 receptor

Tumor necrosis factor alpha-induced apoptosis in astrocytes is prevented by the activation of P2Y6, but not P2Y4 nucleotide receptors

P2X receptors in sensory neurones

Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption

Osteoclast differentiation and activation

Calcium oscillations increase the efficiency and specificity of gene expression

NF-kappaB at the crossroads of life and death

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16909-16915

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10.1074/JBC.M410764200

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17

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280

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2005-02-18T00:00:00Z

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15722352

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