Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival.
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The neuronal K-Cl cotransporter KCC2 influences postsynaptic AMPA receptor content and lateral diffusion in dendritic spinesExpanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of DiseasesCurrent view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2KCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX.Chloride Sensing by WNK1 Involves Inhibition of AutophosphorylationMolecular and evolutionary insights into the structural organization of cation chloride cotransportersTransgenic mouse lines for non-invasive ratiometric monitoring of intracellular chloride.Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transportersAcute TrkB inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemiaKCC2 downregulation facilitates epileptic seizures.3-Nitropropionic acid-induced ischemia tolerance in the rat brain is mediated by reduced metabolic activity and cerebral blood flowWNK1/HSN2 mutation in human peripheral neuropathy deregulates KCC2 expression and posterior lateral line development in zebrafish (Danio rerio)Prenatal Hypoxia-Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone.Detrimental effect of post Status Epilepticus treatment with ROCK inhibitor Y-27632 in a pilocarpine model of temporal lobe epilepsy.A noninvasive optical approach for assessing chloride extrusion activity of the K-Cl cotransporter KCC2 in neuronal cells.Improved method for efficient imaging of intracellular Cl(-) with Cl-Sensor using conventional fluorescence setup.Calibration and functional analysis of three genetically encoded Cl(-)/pH sensors.Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2Molecular probes and switches for functional analysis of receptors, ion channels and synaptic networks.Imaging and serum biomarkers reflecting the functional efficacy of extended erythropoietin treatment in rats following infantile traumatic brain injury.Is it safe to use a diuretic to treat seizures early in development ?Timing of developmental sequences in different brain structures: physiological and pathological implications.K-Cl cotransporter KCC2--a moonlighting protein in excitatory and inhibitory synapse development and function.Molecular cloning and biochemical characterization of two cation chloride cotransporter subfamily members of Hydra vulgaris.Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus.Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.Chloride co-transporters as possible therapeutic targets for stroke.WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2Intracellular chloride concentration influences the GABAA receptor subunit composition.Contribution of Resting Conductance, GABAA-Receptor Mediated Miniature Synaptic Currents and Neurosteroid to Chloride Homeostasis in Central Neurons.Transient increase in neuronal chloride concentration by neuroactive aminoacids released from glioma cells.Commentary: Chloride Regulation: A Dynamic Equilibrium Crucial for Synaptic Inhibition.Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain.Molecular architecture of potassium chloride co-transporter KCC2.The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.NKCC1-Mediated GABAergic Signaling Promotes Postnatal Cell Death in Neocortical Cajal-Retzius Cells.BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes.Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy.Chlorpyrifos Leads to Oxidative Stress-Induced Death of Hippocampal Cells in Vitro
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P2860
Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival.
description
2011 nî lūn-bûn
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2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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name
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@en
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@nl
type
label
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@en
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@nl
prefLabel
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@en
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@nl
P2093
P2860
P50
P1476
Knocking down of the KCC2 in r ...... compromises neuronal survival.
@en
P2093
Hélène Becq
Ilona Chudotvorova
Michael Schaefer
Olena Gubkina
Piotr Bregestovski
Severine Corby
P2860
P304
P356
10.1113/JPHYSIOL.2010.203703
P407
P577
2011-03-21T00:00:00Z