Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis.
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Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signalingInteraction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisFunctional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic proteinThe vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein BaxVaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligandsHost-Cell Survival and Death During Chlamydia InfectionStructure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2Structural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1LStructural basis of Deerpox virus-mediated inhibition of apoptosisThe N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation.Caspase-dependent inhibition of mousepox replication by gzmB.Vaccinia virus protein F1L is a caspase-9 inhibitorInduction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa.Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigensN1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection.Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus.Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathwayVariola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim.White spot syndrome virus induces metabolic changes resembling the warburg effect in shrimp hemocytes in the early stage of infectionPhylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.Direct comparison of antigen production and induction of apoptosis by canarypox virus- and modified vaccinia virus ankara-human immunodeficiency virus vaccine vectorsSheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins.Mechanisms of apoptosis regulation by viral oncogenes in infection and tumorigenesis.The orthopoxvirus 68-kilodalton ankyrin-like protein is essential for DNA replication and complete gene expression of modified vaccinia virus Ankara in nonpermissive human and murine cells.How vaccinia virus has evolved to subvert the host immune response.Innate immune recognition of poxviral vaccine vectors.The vaccinia virus-encoded Bcl-2 homologues do not act as direct Bax inhibitors.Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis.Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activationVaccinia virus encodes a novel inhibitor of apoptosis that associates with the apoptosome.Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis.Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis.Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria.The Bcl-2 Family in Host-Virus Interactions.Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection.Fowlpox virus encodes a Bcl-2 homologue that protects cells from apoptotic death through interaction with the proapoptotic protein Bak.Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis.E3L and F1L Gene Functions Modulate the Protective Capacity of Modified Vaccinia Virus Ankara Immunization in Murine Model of Human Smallpox.
P2860
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P2860
Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@en
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@nl
type
label
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@en
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@nl
prefLabel
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@en
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@nl
P2093
P2860
P356
P1476
Modified vaccinia virus Ankara ...... ck virus-associated apoptosis.
@en
P2093
Fischer SF
Holzapfel J
Kvansakul M
P2860
P2888
P304
P356
10.1038/SJ.CDD.4401718
P50
P577
2006-01-01T00:00:00Z
P6179
1012096704