A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
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Hair cell bundles: flexoelectric motors of the inner earIntegrating the biophysical and molecular mechanisms of auditory hair cell mechanotransductionMotor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membraneMultiple mutations of MYO1A, a cochlear-expressed gene, in sensorineural hearing lossThe myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signalingRefinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner earMulti-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereociliaMyo1c is designed for the adaptation response in the inner earMechanical amplification by hair cells in the semicircular canalsCadherins and mechanotransduction by hair cellsMaking an effort to listen: mechanical amplification in the earCalmodulin binding to recombinant myosin-1c and myosin-1c IQ peptides.Sensing sound: molecules that orchestrate mechanotransduction by hair cellsUse the force: membrane tension as an organizer of cell shape and motilityDiverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing.Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.Disruption of Myosin 1e promotes podocyte injuryLocalization of myosin 1b to actin protrusions requires phosphoinositide bindingMyosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransductionBiochemical and motile properties of Myo1b splice isoformsA model of stereocilia adaptation based on single molecule mechanical studies of myosin IThe very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles.Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cellsTMHS is an integral component of the mechanotransduction machinery of cochlear hair cellsDevelopmental acquisition of sensory transduction in hair cells of the mouse inner earThe physiology of mechanoelectrical transduction channels in hearing.Genetics of auditory mechano-electrical transduction.The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative geneSound strategies for hearing restoration.Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochleaFast adaptation in vestibular hair cells requires myosin-1c activity.Sensory transduction and adaptation in inner and outer hair cells of the mouse auditory system.Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genesA mutation in the cdh23 gene causes age-related hearing loss in Cdh23(nmf308/nmf308) miceFilling the silent void: genetic therapies for hearing impairment.Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.Molecular biology of hearing.Linking genes underlying deafness to hair-bundle development and function.
P2860
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P2860
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
@en
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
@nl
type
label
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
@en
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
@nl
prefLabel
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
@en
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.
@nl
P2093
P50
P1433
P1476
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells
@en
P2093
Jeffrey R Holt
Kavita Shah
Kevan M Shokat
Peter G Gillespie
Susan K H Gillespie
P304
P356
10.1016/S0092-8674(02)00629-3
P407
P577
2002-02-01T00:00:00Z