Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation.
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Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patientsGenomic variability within an organism exposes its cell lineage treeDNA polymerase delta is required for human mismatch repair in vitroMutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repairSimple tandem DNA repeats and human genetic diseaseGenetic reconstruction of individual colorectal tumor historiesColorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicity.The immunogenicity of colorectal cancers with high-degree microsatellite instabilityMolecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesisMultiple primary colorectal cancer: Individual or familial predisposition?MicroRNAs as growth regulators, their function and biomarker status in colorectal cancerThe double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformationMolecular basis of genetic instability of triplet repeatsMethylation mattersStepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancersMSH2 deficient mice are viable and susceptible to lymphoid tumoursHeads or tails: L1 insertion-associated 5' homopolymeric sequencesColorectal adenoma and cancer divergence. Evidence of multilineage progressionGene Expression Variations in Microsatellite Stable and Unstable Colon Cancer CellsClonal mutations in primary human glial tumors: evidence in support of the mutator hypothesisProducts of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coliMismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseasesMutated gene-specific phenotypes of dinucleotide repeat instability in human colorectal carcinoma cell lines deficient in DNA mismatch repair.American Joint Committee on Cancer Prognostic Factors Consensus Conference: Colorectal Working Group.The clonal origin and clonal evolution of epithelial tumours.Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype.Islands of complex DNA are widespread in Drosophila centric heterochromatin.The protective role of symmetric stem cell division on the accumulation of heritable damageMolecular inversion probe analysis of gene copy alterations reveals distinct categories of colorectal carcinomaA molecular rationale for the how, when and why of colorectal cancer screening.Talking tumours: histories from sequencesUnderstanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.Host susceptibility to cancer progression.The mutation rate and cancer.The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome.Functional overlap in mismatch repair by human MSH3 and MSH6.Microsatellite instability and its relevance to cutaneous tumorigenesis.Clinical implications of microsatellite instability in T1 colorectal cancerGenetic profiling of colon cancer.Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer.
P2860
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P2860
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Genomic instability in repeate ...... persists after transformation.
@en
Genomic instability in repeate ...... persists after transformation.
@nl
type
label
Genomic instability in repeate ...... persists after transformation.
@en
Genomic instability in repeate ...... persists after transformation.
@nl
prefLabel
Genomic instability in repeate ...... persists after transformation.
@en
Genomic instability in repeate ...... persists after transformation.
@nl
P2093
P2860
P356
P1433
P1476
Genomic instability in repeate ...... persists after transformation.
@en
P2093
P2860
P2888
P304
P356
10.1038/NG0394-273
P407
P577
1994-03-01T00:00:00Z