about
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiencySP100 inhibits ETS1 activity in primary endothelial cellsThe immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell deathPyogenic bacterial infections in humans with MyD88 deficiencyCurrent perspectives on systems immunology approaches to rheumatic diseases.Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndromeA transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasmaDetectable changes in the blood transcriptome are present after two weeks of antituberculosis therapyDiarrheagenic Escherichia coli carrying supplementary virulence genes are an important cause of moderate to severe diarrhoeal disease in MexicoAn interactive web application for the dissemination of human systems immunology dataHost immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infectionsData management: it starts at the benchEmerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in OncologyA systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers".CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions.Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.A vision and a prescription for big data-enabled medicine.Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection.Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infectionsAssessing the human immune system through blood transcriptomics.Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro.A genomic approach to human autoimmune diseases.Systemic sclerosis and lupus: points in an interferon-mediated continuum.Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy.Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures.TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus.Copy number loss of the interferon gene cluster in melanomas is linked to reduced T cell infiltrate and poor patient prognosisTranscriptional specialization of human dendritic cell subsets in response to microbial vaccines.Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiencyA novel form of human STAT1 deficiency impairing early but not late responses to interferons.ZnT8-Specific CD4+ T cells display distinct cytokine expression profiles between type 1 diabetes patients and healthy adultsGene expression patterns in blood leukocytes discriminate patients with acute infections.A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancersGenomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosisInterferon signature in the blood in inflammatory common variable immune deficiencyIRF8 mutations and human dendritic-cell immunodeficiency.Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosisHerpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Damien Chaussabel
@ast
Damien Chaussabel
@en
Damien Chaussabel
@es
Damien Chaussabel
@nl
Damien Chaussabel
@sl
type
label
Damien Chaussabel
@ast
Damien Chaussabel
@en
Damien Chaussabel
@es
Damien Chaussabel
@nl
Damien Chaussabel
@sl
prefLabel
Damien Chaussabel
@ast
Damien Chaussabel
@en
Damien Chaussabel
@es
Damien Chaussabel
@nl
Damien Chaussabel
@sl
P106
P1153
6602320002
P21
P31
P496
0000-0002-6131-7242