A three-dimensional pharmacophore model for 5-hydroxytryptamine6 (5-HT6) receptor antagonists.
about
The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's diseaseBinding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies.Investigation of the structure requirement for 5-HT₆ binding affinity of arylsulfonyl derivatives: a computational studyCombination of Pharmacophore Matching, 2D Similarity Search, and In Vitro Biological Assays in the Selection of Potential 5-HT6 Antagonists from Large Commercial Repositories.First chemical feature-based pharmacophore modeling of potent retinoidal retinoic acid metabolism blocking agents (RAMBAs): identification of novel RAMBA scaffolds.The medicinal chemistry of 5-HT6 receptor ligands with a focus on arylsulfonyltryptamine analogs.Role of serotonin in Alzheimer's disease: a new therapeutic target?Serotonin 5-HT6 Receptor Antagonists in Alzheimer's Disease: Therapeutic Rationale and Current Development Status.A new serotonin 5-HT6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding.Design, synthesis and pharmacological evaluation of indolylsulfonamide amines as potent and selective 5-HT6 receptor antagonists.Synthesis and biological evaluation of novel N1-phenylsulphonyl indole derivatives as potent and selective 5-HT6R ligands for the treatment of cognitive disorders.Extended N-Arylsulfonylindoles as 5-HT₆ Receptor Antagonists: Design, Synthesis & Biological Evaluation.
P2860
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P2860
A three-dimensional pharmacophore model for 5-hydroxytryptamine6 (5-HT6) receptor antagonists.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
A three-dimensional pharmacoph ...... (5-HT6) receptor antagonists.
@en
A three-dimensional pharmacophore model for 5-hydroxytryptamine6
@nl
type
label
A three-dimensional pharmacoph ...... (5-HT6) receptor antagonists.
@en
A three-dimensional pharmacophore model for 5-hydroxytryptamine6
@nl
prefLabel
A three-dimensional pharmacoph ...... (5-HT6) receptor antagonists.
@en
A three-dimensional pharmacophore model for 5-hydroxytryptamine6
@nl
P50
P356
P1476
A three-dimensional pharmacoph ...... 6 (5-HT6) receptor antagonists
@en
P2093
Arantxa Sanz
Tania de la Fuente
P304
P356
10.1021/JM050247C
P407
P577
2005-06-01T00:00:00Z