JNK1 but not JNK2 promotes the development of steatohepatitis in mice. - Wikidata - wikimedia - TriplyDB

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

http://www.wikidata.org/entity/Q46865809

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Stress kinases in the modulation of metabolism and energy balance Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications Genetically modified mouse models for the study of nonalcoholic fatty liver disease Systematic review on the treatment of pentoxifylline in patients with non-alcoholic fatty liver disease Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells Endoplasmic reticulum stress activates the hepatic activator protein 1 complex via mitogen activated protein kinase-dependent signaling pathways A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches Inflammation in nonalcoholic steatohepatitis.Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells.Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice.Prevention of steatosis by hepatic JNK1 Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation.Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death.The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD).Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction.Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis Hepatocyte death: a clear and present danger.JNK regulation of hepatic manifestations of the metabolic syndrome.Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling.INTRACELLULAR SIGNALING BY BILE ACIDS.Hepatoprotective and antioxidant activities of extracts from Salvia-Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice.Non alcoholic steatohepatitis a precursor for hepatocellular carcinoma development.Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice.Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK.Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27.Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity.Mechanisms of lipotoxicity in NAFLD and clinical implications A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury.Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice.Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice.Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis.Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis.Voluntary Exercise Can Ameliorate Insulin Resistance by Reducing iNOS-Mediated S-Nitrosylation of Akt in the Liver in Obese Rats.Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway.

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P2860

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

http://www.wikidata.org/entity/Q46865809

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

@yue

2006年學術文章

@zh-hant

name

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

@en

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

@nl

type

label

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

@en

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

@nl

prefLabel

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

@en

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

@nl

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JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

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Jay H Lefkowitch

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Mark J Czaja

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Philipp E Scherer

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Raina M Rigoli

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Rajat Singh

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Yongjun Wang

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163-172

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10.1002/HEP.20999

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1

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Jörn M Schattenberg

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2006-01-01T00:00:00Z

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Steatohepatitis