New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme. - Wikidata - wikimedia - TriplyDB

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

http://www.wikidata.org/entity/Q46886493

about

Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death.Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria Catalytic antioxidants to treat amyotropic lateral sclerosis.Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor Roles of reactive oxygen and nitrogen species in pain Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate.Determination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics.Advances in the Pathogenesis of Adhesion Development: The Role of Oxidative Stress.Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: voltammetric and chronocoulometric study of protolytic and redox equilibria.A dual enzyme microgel with high antioxidant ability based on engineered seleno-ferritin and artificial superoxide dismutase.Unconventional neuroprotection against Ca2+ -dependent insults by metalloporphyrin catalytic antioxidants.Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues.

P2860

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P2860

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

http://www.wikidata.org/entity/Q46886493

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh-hant

name

New PEG-ylated Mn

@nl

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

@en

type

label

New PEG-ylated Mn

@nl

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

@en

prefLabel

New PEG-ylated Mn

@nl

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

@en

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P1433

Dalton Transactions

P1476

New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.

@en

P2093

Ayako Okado-Matsumoto

http://www.w3.org/2001/XMLSchema#string

Bruce Bondurant

http://www.w3.org/2001/XMLSchema#string

Ines Batinić-Haberle

http://www.w3.org/2001/XMLSchema#string

Irwin Fridovich

http://www.w3.org/2001/XMLSchema#string

Ivan Spasojević

http://www.w3.org/2001/XMLSchema#string

Mark W Dewhirst

http://www.w3.org/2001/XMLSchema#string

Robert D Stevens

http://www.w3.org/2001/XMLSchema#string

Zeljko Vujasković

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P2860

Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple.

Biodistribution and targeting potential of poly(ethylene glycol)-modified gelatin nanoparticles in subcutaneous murine tumor model.

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules.

Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells.

A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.

Regulation of ionizing radiation-induced apoptosis by a manganese porphyrin complex.

p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase.

Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells.

The formation and metabolism of N-hydroxymethyl compounds--IV. Cytotoxicity and antitumour activity of N-hydroxymethylformamide, a putative metabolite of N-methylformamide (NSC 3051).

The potential diagram for oxygen at pH 7.

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617-624

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scholarly article

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10.1039/B513761F

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4

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2005-12-19T00:00:00Z

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16402149

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