Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells. - Wikidata - wikimedia - TriplyDB

Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.

Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.

http://www.wikidata.org/entity/Q41422364

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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5.Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential Microenvironmental regulation of glioblastoma radioresponse.Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.Redox processes in neurodegenerative disease involving reactive oxygen species Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).Radiation countermeasure agents: an update.Modifying radiation damage.Manganese superoxide dismutase, MnSOD and its mimics Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.Evaluation of the anti-oxidant properties of a SOD-mimic Mn-complex in activated macrophages.Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide.High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli Determination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics.Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+).Radio-protective effect and mechanism of 4-Acetamido-2,2,6,6- tetramethylpiperidin-1-oxyl in HUVEC cells.Effect of different manganese concentrations during in vitro maturation of bovine oocytes on DNA integrity of cumulus cells and subsequent embryo development.Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation.

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Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.

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Free Radical Biology and Medicine

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

ATM and related protein kinases: safeguarding genome integrity

Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple.

A risk-benefit assessment of amifostine in cytoprotection.

The use of transgenic and mutant mice to study oxygen free radical metabolism.

Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene.

Early diagnosis of ataxia-telangiectasia using radiosensitivity testing.

Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice.

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

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