Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
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Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.Single and Multiple Gene Manipulations in Mouse Models of Human CancerPhosphatase and Tensin Homologue: Novel Regulation by Developmental SignalingThe androgen receptor and stem cell pathways in prostate and bladder cancers (review)PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility.Biology of urothelial tumorigenesis: insights from genetically engineered mice.Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancerLkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladderβ-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.Identification of prognostic gene signatures of glioblastoma: a study based on TCGA data analysis.Modelling bladder cancer in mice: opportunities and challenges.Pten in mouse vaginaA PTEN translational isoform has PTEN-like activity.Inactivation of the retinoblastoma gene yields a mouse model of malignant colorectal cancerAntigen-induced Pten gene deletion in T cells exacerbates neuropathology in experimental autoimmune encephalomyelitis.Expression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy.pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.FGFR3b Extracellular Loop Mutation Lacks Tumorigenicity In Vivo but Collaborates with p53/pRB Deficiency to Induce High-grade Papillary Urothelial Carcinoma.Inactivation of p53 and Pten promotes invasive bladder cancerPten haploinsufficiency accelerates formation of high-grade astrocytomasMolecular genetics of bladder cancer: Emerging mechanisms of tumor initiation and progression.Exploring molecular genetics of bladder cancer: lessons learned from mouse modelsDiscussion of PARP inhibitors in cancer therapy.Phosphatidylinositol 3'-kinase, mTOR, and glycogen synthase kinase-3β mediated regulation of p21 in human urothelial carcinoma cellsThe role of WNT signalling in urothelial cell carcinoma.Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesisInsights from animal models of bladder cancer: recent advances, challenges, and opportunities.Overexpression of DJ-1 and HSP90α, and loss of PTEN associated with invasive urothelial carcinoma of urinary bladder: Possible prognostic markers.Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in micePTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.Unique roles of estrogen-dependent Pten control in epithelial cell homeostasis of mouse vagina.Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes.PTEN gene silencing prevents HIV-1 gp120(IIIB)-induced degeneration of striatal neurons.
P2860
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P2860
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Pten deficiency activates dist ...... s in a tissue-specific manner.
@en
Pten deficiency activates dist ...... s in a tissue-specific manner.
@nl
type
label
Pten deficiency activates dist ...... s in a tissue-specific manner.
@en
Pten deficiency activates dist ...... s in a tissue-specific manner.
@nl
prefLabel
Pten deficiency activates dist ...... s in a tissue-specific manner.
@en
Pten deficiency activates dist ...... s in a tissue-specific manner.
@nl
P2093
P1433
P1476
Pten deficiency activates dist ...... s in a tissue-specific manner.
@en
P2093
David W Liu
Junying Yuan
Lina I Yoo
Roderick T Bronson
Sandrine Le Vu
P304
P356
10.1158/0008-5472.CAN-05-1986
P407
P577
2006-02-01T00:00:00Z