Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.
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Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in AplysiaNeurotrophic factors in Alzheimer’s disease: role of axonal transportThe novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport.A pilot proteomic study of amyloid precursor interactors in Alzheimer's diseaseMutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degenerationThe amyloid-beta precursor protein: integrating structure with biological functionDissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's diseaseSyntabulin-mediated anterograde transport of mitochondria along neuronal processesThe amyloid precursor protein: beyond amyloidEvolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila.The presenilinsAnalysis of Amyloid Precursor Protein Function in Drosophila melanogasterBiomaterials for the Treatment of Alzheimer's DiseaseThe Crossroads of Synaptic Growth Signaling, Membrane Traffic and Neurological Disease: Insights from DrosophilaAxonal transport disruption in peripheral nerve disease: From Jack's discoveries as a resident to recent contributionsLoss of Polo ameliorates APP-induced Alzheimer's disease-like symptoms in DrosophilaGr33a modulates Drosophila male courtship preferenceThe Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in DrosophilaA γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APPDisruption of axonal transport perturbs bone morphogenetic protein (BMP)--signaling and contributes to synaptic abnormalities in two neurodegenerative diseasesNeurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding proteinNebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signalingAmyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegenerationSpatial and temporal characteristics of normal and perturbed vesicle transportEpigenetic Changes in Neurodegenerative DiseasesAxonal Transport and Neurodegeneration: How Marine Drugs Can Be Used for the Development of TherapeuticsModeling the complex pathology of Alzheimer's disease in DrosophilaOrganically modified silica nanoparticles are biocompatible and can be targeted to neurons in vivoInteraction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascadeThe autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.Axonal transport and neurodegenerative disease: can we see the elephant?Mechanical dynamics in live cells and fluorescence-based force/tension sensorsRotenone-dependent changes of anterograde motor protein expression and mitochondrial mobility in brain areas related to neurodegenerative diseasesA peptide zipcode sufficient for anterograde transport within amyloid precursor protein.Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model.Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.β-Amyloid impairs axonal BDNF retrograde trafficking.Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in DrosophilaSubpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles.Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of alzheimer's disease.
P2860
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P2860
Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Disruption of axonal transport ...... otein mutations in Drosophila.
@en
Disruption of axonal transport ...... otein mutations in Drosophila.
@nl
type
label
Disruption of axonal transport ...... otein mutations in Drosophila.
@en
Disruption of axonal transport ...... otein mutations in Drosophila.
@nl
prefLabel
Disruption of axonal transport ...... otein mutations in Drosophila.
@en
Disruption of axonal transport ...... otein mutations in Drosophila.
@nl
P1433
P1476
Disruption of axonal transport ...... rotein mutations in Drosophila
@en
P2093
L S Goldstein
P304
P356
10.1016/S0896-6273(01)00496-2
P407
P577
2001-11-01T00:00:00Z