Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
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A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism.Neonatal Seizures: Impact on Neurodevelopmental OutcomesPhysiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockoutsStress, seizures, and hypothalamic-pituitary-adrenal axis targets for the treatment of epilepsySearching for new targets for treatment of pediatric epilepsyMolecular mechanisms of antiseizure drug activity at GABAA receptorsDifferences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures.Development of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizuresThe potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transportersAcute TrkB inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemiaNeonatal seizures: advances in mechanisms and managementNKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility.Neonatal seizures: an update on mechanisms and managementEpileptogenesis in the immature brain: emerging mechanisms.Developmental factors in the pathogenesis of neonatal seizuresSynergistic neuroprotective therapies with hypothermia.Chloride regulation in the pain pathwayBumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus.Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1.Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn SeizuresSubunit composition of neurotransmitter receptors in the immature and in the epileptic brain.Sex dimorphism in seizure-controlling networks.Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures.Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizuresPre-Clinical Models of Acquired Neonatal Seizures: Differential Effects of Injury on Function of Chloride Co-Transporters.Altered GABA signaling in early life epilepsies.Loss of cation-chloride cotransporter expression in preterm infants with white matter lesions: implications for the pathogenesis of epilepsyAcute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis.Carts, Horses, and Push-Pull Regulation of EGABA in Neonatal SeizuresRosiglitazone Suppresses In Vitro Seizures in Hippocampal Slice by Inhibiting Presynaptic Glutamate Release in a Model of Temporal Lobe EpilepsyMolecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain.Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia.Unexpected extra-renal effects of loop diuretics in the preterm neonateNeonatal encephalopathy, MRI lesions, and later epilepsy: no harm, no foul?Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics.Autism, oxytocin and interoception
P2860
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P2860
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
@en
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
@nl
type
label
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
@en
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
@nl
prefLabel
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
@en
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
@nl
P2860
P356
P1433
P1476
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model
@en
P2093
Kevin J Staley
Volodymyr I Dzhala
P2860
P304
P356
10.1002/ANA.21229
P50
P577
2008-02-01T00:00:00Z