Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein.
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The stoichiometry and biophysical properties of the Kv4 potassium channel complex with K+ channel-interacting protein (KChIP) subunits are variable, depending on the relative expression levelModulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunitsMultiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like propertiesComplete 3D visualization of primate striosomes by KChIP1 immunostainingStructural Insights into KChIP4a Modulation of Kv4.3 InactivationTwo arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamilyPalmitoylation of KChIP splicing variants is required for efficient cell surface expression of Kv4.3 channelsS-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivationKv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neuronesInhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.Mechanism of the modulation of Kv4:KChIP-1 channels by external K+Enhancing the fidelity of neurotransmission by activity-dependent facilitation of presynaptic potassium currents.A novel DPP6 isoform (DPP6-E) can account for differences between neuronal and reconstituted A-type K(+) channels.Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons.Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.The link between ion permeation and inactivation gating of Kv4 potassium channels.Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexesGenome wide response to dietary tetradecylthioacetic acid supplementation in the heart of Atlantic Salmon (Salmo salar L).Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells.Time- and voltage-dependent components of Kv4.3 inactivation.Modulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806.DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channelsSubgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit.A-type potassium currents in smooth muscle.Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings, with an Application to Human Uterine Smooth Muscle Cells.Potassium channels and uterine function.Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice.A dipeptidyl aminopeptidase-like protein remodels gating charge dynamics in Kv4.2 channels.Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels.Gating charge immobilization in Kv4.2 channels: the basis of closed-state inactivation.Functionally active t1-t1 interfaces revealed by the accessibility of intracellular thiolate groups in kv4 channelsKv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neuronsModification of K+ channel-drug interactions by ancillary subunits.Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channelsThe neuronal Kv4 channel complex.The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.Weighing the evidence for a ternary protein complex mediating A-type K+ currents in neurons.Closed-state inactivation in Kv4.3 isoforms is differentially modulated by protein kinase C.
P2860
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P2860
Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein.
description
2002 nî lūn-bûn
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2002年の論文
@ja
2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
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name
Remodelling inactivation gatin ...... eight calcium-binding protein.
@en
Remodelling inactivation gatin ...... eight calcium-binding protein.
@nl
type
label
Remodelling inactivation gatin ...... eight calcium-binding protein.
@en
Remodelling inactivation gatin ...... eight calcium-binding protein.
@nl
prefLabel
Remodelling inactivation gatin ...... eight calcium-binding protein.
@en
Remodelling inactivation gatin ...... eight calcium-binding protein.
@nl
P2093
P2860
P1476
Remodelling inactivation gatin ...... eight calcium-binding protein.
@en
P2093
Edward J Beck
Kenneth J Rhodes
Manuel Covarrubias
Mark Bowlby
W Frank An
P2860
P304
P356
10.1113/JPHYSIOL.2001.013127
P407
P577
2002-02-01T00:00:00Z