Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: a molecular dynamics simulation study.
about
Large scale characterization of the LC13 TCR and HLA-B8 structural landscape in reaction to 172 altered peptide ligands: a molecular dynamics simulation studyA comparative approach linking molecular dynamics of altered peptide ligands and MHC with in vivo immune responsesThe Peptide-Receptive Transition State of MHC Class I Molecules: Insight from Structure and Molecular DynamicsConformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchangeExploring protein dynamics space: the dynasome as the missing link between protein structure and function.Enthalpy-entropy compensation and cooperativity as thermodynamic epiphenomena of structural flexibility in ligand-receptor interactionsDynamics based alignment of proteins: an alternative approach to quantify dynamic similarityCharacterization of structural features controlling the receptiveness of empty class II MHC molecules.T-cell epitope prediction and immune complex simulation using molecular dynamics: state of the art and persisting challenges.For many but not for all: how the conformational flexibility of the peptide/MHCII complex shapes epitope selectionStructural and dynamical insights on HLA-DR2 complexes that confer susceptibility to multiple sclerosis in Sardinia: a molecular dynamics simulation studyEarly relaxation dynamics in the LC 13 T cell receptor in reaction to 172 altered peptide ligands: a molecular dynamics simulation studyIs an intuitive convergence definition of molecular dynamics simulations solely based on the root mean square deviation possible?The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study.The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM.Consensus classification of human leukocyte antigen class II proteins.Conformational variation in structures of classical and non-classical MHCII proteins and functional implications.HLA-DM: arbiter conformationis.Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes.Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange.Current status and future challenges in T-cell receptor/peptide/MHC molecular dynamics simulations.Mechanistic understanding and significance of small peptides interaction with MHC class II molecules for therapeutic applications.F pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins.A novel family of human leukocyte antigen class II receptors may have its origin in archaic human speciesMajor Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.Energetic and flexibility properties captured by long molecular dynamics simulations of a membrane-embedded pMHCII-TCR complex.MHC class II complexes sample intermediate states along the peptide exchange pathway.Exploring peptide/MHC detachment processes using hierarchical natural move Monte Carlo.Modeling Functional Motions of Biological Systems by Customized Natural Moves.A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing.Antigenic peptide molecular recognition by the DRB1-DQB1 haplotype modulates multiple sclerosis susceptibility.Differential geometric analysis of alterations in MH α-helicesEfficient estimation of binding free energies between peptides and an MHC class II molecule using coarse-grained molecular dynamics simulations with a weighted histogram analysis method.The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling
P2860
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P2860
Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: a molecular dynamics simulation study.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Flexibility of the MHC class I ...... lar dynamics simulation study.
@en
Flexibility of the MHC class I ...... lar dynamics simulation study.
@nl
type
label
Flexibility of the MHC class I ...... lar dynamics simulation study.
@en
Flexibility of the MHC class I ...... lar dynamics simulation study.
@nl
prefLabel
Flexibility of the MHC class I ...... lar dynamics simulation study.
@en
Flexibility of the MHC class I ...... lar dynamics simulation study.
@nl
P356
P1433
P1476
Flexibility of the MHC class I ...... lar dynamics simulation study.
@en
P2093
Rakina Yaneva
P2860
P356
10.1002/BIP.21078
P577
2009-01-01T00:00:00Z