Glycoprotein hormone assembly in the endoplasmic reticulum: II. Multiple roles of a redox sensitive beta-subunit disulfide switch.
about
Structure-function relationships of glycoprotein hormones and their subunits' ancestors.Synthesis and secretion of gonadotropins including structure-function correlates.Comparative structure analyses of cystine knot-containing molecules with eight aminoacyl ring including glycoprotein hormones (GPH) alpha and beta subunits and GPH-related A2 (GPA2) and B5 (GPB5) molecules.Only a portion of the small seatbelt loop in human choriogonadotropin appears capable of contacting the lutropin receptor.Use of protein knobs to characterize the position of conserved alpha-subunit regions in lutropin receptor complexes.Glycoprotein hormone assembly in the endoplasmic reticulum: I. The glycosylated end of human alpha-subunit loop 2 is threaded through a beta-subunit hole.Human lutropin (hLH) and choriogonadotropin (CG) are assembled by different pathways: a model of hLH assembly.Glycoprotein hormone assembly in the endoplasmic reticulum: III. The seatbelt and its latch site determine the assembly pathway.Glycoprotein hormone assembly in the endoplasmic reticulum: IV. Probable mechanism of subunit docking and completion of assembly.
P2860
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P2860
Glycoprotein hormone assembly in the endoplasmic reticulum: II. Multiple roles of a redox sensitive beta-subunit disulfide switch.
description
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name
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@en
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@nl
type
label
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@en
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@nl
prefLabel
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@en
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@nl
P2093
P2860
P356
P1476
Glycoprotein hormone assembly ...... beta-subunit disulfide switch.
@en
P2093
Donghui Cao
Michael P Bernard
Rebecca V Myers
William R Moyle
Yongna Xing
P2860
P304
35437-35448
P356
10.1074/JBC.M403053200
P407
P577
2004-05-25T00:00:00Z