Coupling between global dynamics and signal transduction pathways: a mechanism of allostery for chaperonin GroEL.
about
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewModeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimerQuantifying Correlations Between Allosteric Sites in Thermodynamic EnsemblesComputational model for protein unfolding simulation.Computational modeling of allosteric regulation in the hsp90 chaperones: a statistical ensemble analysis of protein structure networks and allosteric communications.Allosteric pathway identification through network analysis: from molecular dynamics simulations to interactive 2D and 3D graphs.Coherent conformational degrees of freedom as a structural basis for allosteric communication.Change in allosteric network affects binding affinities of PDZ domains: analysis through perturbation response scanning.Computational modeling of allosteric communication reveals organizing principles of mutation-induced signaling in ABL and EGFR kinases.The energy landscape analysis of cancer mutations in protein kinasesMethionine sulfoxides on prion protein Helix-3 switch on the alpha-fold destabilization required for conversion.Allosteric transitions of supramolecular systems explored by network models: application to chaperonin GroEL.Computational study of the resistance shown by the subtype B/HIV-1 protease to currently known inhibitors.Using entropy maximization to understand the determinants of structural dynamics beyond native contact topologyNormal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.Investigating dynamic and energetic determinants of protein nucleic acid recognition: analysis of the zinc finger zif268-DNA complexes.Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms.Exploring residue component contributions to dynamical network models of allosteryAllosteric communication across the native and mutated KIT receptor tyrosine kinase.Differential effects of CSF-1R D802V and KIT D816V homologous mutations on receptor tertiary structure and allosteric communicationLong-distance correlations of rhinovirus capsid dynamics contribute to uncoating and antiviral activity.Weak intra-ring allosteric communications of the archaeal chaperonin thermosome revealed by normal mode analysisSystematic multiscale parameterization of heterogeneous elastic network models of proteinsMultiple pathways promote dynamical coupling between catalytic domains in Escherichia coli prolyl-tRNA synthetase.Vibrational dynamics of icosahedrally symmetric biomolecular assemblies compared with predictions based on continuum elasticityCoarse-grained modeling of allosteric regulation in protein receptorsThe spatial structure of cell signaling systems.Comparative Study of Elastic Network Model and Protein Contact Network for Protein Complexes: The Hemoglobin Case.The Role of Conformational Dynamics and Allostery in the Disease Development of Human Ferritin.On the functional significance of soft modes predicted by coarse-grained models for membrane proteins.Stability and folding behavior analysis of zinc-finger using simple models.Nhs: network-based hierarchical segmentation for cryo-electron microscopy density maps.Normal-mode-analysis-guided investigation of crucial intersubunit contacts in the cAMP-dependent gating in HCN channels.Study of Functional and Allosteric Sites in Protein SuperfamiliesExploiting conformational dynamics in drug discovery: design of C-terminal inhibitors of Hsp90 with improved activities.Toward understanding allosteric signaling mechanisms in the ATPase domain of molecular chaperones.Metal-binding sites are designed to achieve optimal mechanical and signaling properties.MDN: A Web Portal for Network Analysis of Molecular Dynamics Simulations.Light on the structural communication in Ras GTPases.Design of Elastic Networks with Evolutionary Optimized Long-Range Communication as Mechanical Models of Allosteric Proteins.
P2860
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P2860
Coupling between global dynamics and signal transduction pathways: a mechanism of allostery for chaperonin GroEL.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Coupling between global dynami ...... llostery for chaperonin GroEL.
@en
Coupling between global dynami ...... llostery for chaperonin GroEL.
@nl
type
label
Coupling between global dynami ...... llostery for chaperonin GroEL.
@en
Coupling between global dynami ...... llostery for chaperonin GroEL.
@nl
prefLabel
Coupling between global dynami ...... llostery for chaperonin GroEL.
@en
Coupling between global dynami ...... llostery for chaperonin GroEL.
@nl
P2093
P356
P1433
P1476
Coupling between global dynami ...... llostery for chaperonin GroEL.
@en
P2093
Chakra Chennubhotla
Ivet Bahar
Zheng Yang
P304
P356
10.1039/B717819K
P577
2008-02-20T00:00:00Z