Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts.
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SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epitheliumAdeno-associated virus vector integrationGlucose deprivation contributes to the development of KRAS pathway mutations in tumor cellsRestoration of mitochondria function as a target for cancer therapyHIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA ReplicationTumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines.Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection.Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes.Chronic inhibition of tumor cell-derived VEGF enhances the malignant phenotype of colorectal cancer cells.SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production.The role of the HIF-1α transcription factor in increased cell division at physiological oxygen tensions.The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.A protein therapeutic modality founded on molecular regulation.HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cellsHypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways.Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells.Combination therapy targeting cancer metabolism.Differential Regulation of Gene Expression of Alveolar Epithelial Cell Markers in Human Lung Adenocarcinoma-Derived A549 Clones.Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy.Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal CancerKnockdown of hypoxia-inducible factor-1α accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell linesMechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1.A Modular Assembly Platform for Rapid Generation of DNA Constructs.Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.Intracrine VEGF Signaling Mediates the Activity of Prosurvival Pathways in Human Colorectal Cancer Cells.The TIP60 Complex Is a Conserved Coactivator of HIF1AHIF-1alpha determines the metastatic potential of gastric cancer cells.Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5.HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurationsNQO1 inhibits proteasome-mediated degradation of HIF-1α.PHD2 in tumour angiogenesis.2-methoxyestradiol in the pathophysiology of endometriosis: focus on angiogenesis and therapeutic potential.Inflammatory pathways in the early steps of colorectal cancer development.Knockdown of Hypoxia-Inducible Factor 1α Improved the Efficacy of Low-Dose Metronomic Chemotherapy of Paclitaxel in Human Colon Cancer Xenografts.COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models.Cytotoxicity of lymphocytes activated by superantigen toxic-shock-syndrome toxin-1 against colorectal cancer LoVo cells.
P2860
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P2860
Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@en
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@nl
type
label
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@en
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@nl
prefLabel
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@en
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@nl
P2093
P1433
P1476
Hypoxia-inducible factor-1alph ...... n cancer cells and xenografts.
@en
P2093
Carlo Rago
Duyen T Dang
Jordan M Cummins
Long H Dang
Sergey V Kantsevoy
P304
P356
10.1158/0008-5472.CAN-05-2887
P407
P577
2006-02-01T00:00:00Z