Dissolved oxygen concentration in serum-free continuous culture affects N-linked glycosylation of a monoclonal antibody.
about
Effects of buffering conditions and culture pH on production rates and glycosylation of clinical phase I anti-melanoma mouse IgG3 monoclonal antibody R24.Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis.Cell culture processes for monoclonal antibody production.Impact of cultivation conditions on N-glycosylation of influenza virus a hemagglutinin produced in MDCK cell culture.Glycosylation and post-translational modification gene expression analysis by DNA microarrays for cultured mammalian cells.Optimization of bioprocess conditions improves production of a CHO cell-derived, bioengineered heparinUnderstanding and Controlling Sialylation in a CHO Fc-Fusion Process.A novel method for monitoring monoclonal antibody production during cell culture.Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by Mammalian cell systems.Genomics and epigenomics of the human glycome.Glycosylation: impact, control and improvement during therapeutic protein production.Glycosylation of monoclonal antibody products: Current status and future prospects.Impact of cell culture on recombinant monoclonal antibody product heterogeneity.Bioreactor environment-sensitive sentinel genes as novel metrics for cell culture scale-down comparability.Modulation of antibody galactosylation through feeding of uridine, manganese chloride, and galactose.Comparisons of optical pH and dissolved oxygen sensors with traditional electrochemical probes during mammalian cell culture.Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture.Enhanced erythropoietin heterogeneity in a CHO culture is caused by proteolytic degradation and can be eliminated by a high glutamine levelCB.Hep-1 hybridoma growth and antibody production using protein-free medium in a hollow fiber bioreactor.Fast development of Pichia pastoris GS115 Mut(+) cultures employing batch-to-batch control and hybrid semi-parametric modeling.Heterogeneous conditions in dissolved oxygen affect N-glycosylation but not productivity of a monoclonal antibody in hybridoma cultures.Cell culture media supplementation of uncommonly used sugars sucrose and tagatose for the targeted shifting of protein glycosylation profiles of recombinant protein therapeutics.Animal Cell Expression Systems.Cell culture media supplementation of infrequently used sugars for the targeted shifting of protein glycosylation profiles.Identifying a robust design space for glycosylation during monoclonal antibody production.Engineer Medium and Feed for Modulating N-Glycosylation of Recombinant Protein Production in CHO Cell Culture.Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity.
P2860
Q30941602-3F3B7EDB-A4D7-482F-BFE9-6B839B85465DQ30987721-85CCF042-F8AF-4E99-B966-5AF227DD5AAFQ34125491-79BC5F8A-EEAC-4EC5-9CFB-A2FEBF2CA53FQ34538848-A1FCD6EF-532D-4009-8183-84DF4C69EAE1Q35783666-77A67773-2496-41EA-8B07-63B3B71D1A1AQ36015630-9683A966-1443-4661-A7F0-7B8039F94036Q36054315-064E31A0-FCA5-4C3C-9748-F6E8A565965EQ37311157-AE62E1C6-192E-4EA3-8DA4-890A18B777B1Q37323542-AFF71C04-148D-41A0-B7B0-B9C0FB02B0EAQ38014677-D2FCEDEC-4456-4208-B8F9-65B7F6D4CA3CQ38126913-8D035B5D-DC88-4571-A5C1-C2DBB759A313Q38807919-75C2633F-D927-4CDB-8E0E-21C3A0BB3521Q38907094-2A7D47CB-5E4C-4B6B-AD48-E0ED0F98C5F0Q39305296-6D008201-44E1-41DE-A2CC-46E287CFEBA6Q39590627-74B2C84C-0BFF-4954-9F7E-32AB8F5BBFA8Q40184332-C55BECCE-A7CD-4559-8DBC-0D399CAC9935Q40853167-30553214-2B74-4E9B-82D2-82AC90239719Q41873068-A8EF704F-8127-4113-8A76-F7BC6E14355AQ41983554-53A07B97-48E0-4EB9-B9CB-9A5E052C7C5EQ44043620-5A155523-33A0-4D4C-B451-87C1D4576CC6Q45078841-B6574D04-4FB7-44D1-B1BE-4898DF163CFAQ46850981-756D0ECB-2893-4A93-8176-8DA7D4C93E79Q47406183-928C6ECB-4000-4BF8-B6DF-A1975653833AQ47598608-8BB4FD6A-F8D5-461C-BBCE-17F73F13EE49Q47656402-364A71C4-A660-45B1-AF82-C36BEE0ECB81Q50880126-E5F95925-0E07-4481-B925-D5A3DC1C2D91Q51607799-7443F65A-94F7-474C-90B8-C3071AE58DF0
P2860
Dissolved oxygen concentration in serum-free continuous culture affects N-linked glycosylation of a monoclonal antibody.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Dissolved oxygen concentration ...... tion of a monoclonal antibody.
@en
Dissolved oxygen concentration ...... tion of a monoclonal antibody.
@nl
type
label
Dissolved oxygen concentration ...... tion of a monoclonal antibody.
@en
Dissolved oxygen concentration ...... tion of a monoclonal antibody.
@nl
prefLabel
Dissolved oxygen concentration ...... tion of a monoclonal antibody.
@en
Dissolved oxygen concentration ...... tion of a monoclonal antibody.
@nl
P2093
P1476
Dissolved oxygen concentration ...... ation of a monoclonal antibody
@en
P2093
P356
10.1016/S0168-1656(98)00044-3
P577
1998-06-01T00:00:00Z