Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically.
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An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release.Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interactionThe human calcium-independent phospholipase A2 gene multiple enzymes with distinct properties from a single geneFYVE zinc-finger proteins in the plant model Arabidopsis thaliana: identification of PtdIns3P-binding residues by comparison of classic and variant FYVE domainsC2 domains from different Ca2+ signaling pathways display functional and mechanistic diversityRegulation of the PI3K pathway through a p85α monomer-homodimer equilibriumThe calcium binding loops of the cytosolic phospholipase A2 C2 domain specify targeting to Golgi and ER in live cellsNovel organization and properties of annexin 2-membrane complexes.High metal concentrations are required for self-association of synaptotagmin II.Amphitropic proteins: regulation by reversible membrane interactions (review).Localization and function of cytosolic phospholipase A2alpha at the Golgi.Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domainsLocation, location, location: compartmentalization of early events in leukotriene biosynthesis.Requirement of calcium binding, myristoylation, and protein-protein interaction for the Copine BON1 function in Arabidopsis.Small heat-shock proteins regulate membrane lipid polymorphism.Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivoInterfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms.Membrane targeting by C1 and C2 domains.X-ray reflectivity studies of cPLA2{alpha}-C2 domains adsorbed onto Langmuir monolayers of SOPCRole of synaptotagmin in Ca2+-triggered exocytosis.Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo.The cPLA2 C2alpha domain in solution: structure and dynamics of its Ca2+-activated and cation-free statesMembrane recognition and targeting by lipid-binding domains.Calcium triggers an intramolecular association of the C2 domains in synaptotagmin.Cytosolic phospholipase A₂: physiological function and role in disease.Role of phosphorylation sites and the C2 domain in regulation of cytosolic phospholipase A2.Interfacial membrane docking of cytosolic phospholipase A2 C2 domain using electrostatic potential-modulated spin relaxation magnetic resonance.Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission.Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity.Constitutively active Rheb induces oncogenic transformation.Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.The C2A domain of synaptotagmin-like protein 3 (Slp3) is an atypical calcium-dependent phospholipid-binding machine: comparison with the C2A domain of synaptotagmin I.The top loops of the C(2) domains from synaptotagmin and phospholipase A(2) control functional specificity.Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling.The cytosolic phospholipase A2 catalytic domain modulates association and residence time at Golgi membranes.A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene.Topography of the prostaglandin endoperoxide H2 synthase-2 in membranes.A structure-function study of the C2 domain of cytosolic phospholipase A2. Identification of essential calcium ligands and hydrophobic membrane binding residues.Real-time assay for monitoring membrane association of lipid-binding domains.
P2860
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P2860
Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Calcium-dependent membrane pen ...... s membranes electrostatically.
@en
Calcium-dependent membrane pen ...... s membranes electrostatically.
@nl
type
label
Calcium-dependent membrane pen ...... s membranes electrostatically.
@en
Calcium-dependent membrane pen ...... s membranes electrostatically.
@nl
prefLabel
Calcium-dependent membrane pen ...... s membranes electrostatically.
@en
Calcium-dependent membrane pen ...... s membranes electrostatically.
@nl
P2860
P356
P1476
Calcium-dependent membrane pen ...... ds membranes electrostatically
@en
P2093
B Davletov
P2860
P304
19093-19096
P356
10.1074/JBC.273.30.19093
P407
P577
1998-07-01T00:00:00Z