Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
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Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicityDOC2B acts as a calcium switch and enhances vesicle fusionPush-and-pull regulation of the fusion pore by synaptotagmin-7The functional significance of synaptotagmin diversity in neuroendocrine secretionDistinct initial SNARE configurations underlying the diversity of exocytosisSnapin facilitates the synchronization of synaptic vesicle fusionCis- and trans-membrane interactions of synaptotagmin-1Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoformsRat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusionSV2B regulates synaptotagmin 1 by direct interactionSynaptojanin cooperates in vivo with endophilin through an unexpected mechanism.Molecular and genetic characterization of the interactions between the Drosophila stoned-B protein and DAP-160 (intersectin).SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells.Conformation and membrane position of the region linking the two C2 domains in synaptotagmin 1 by site-directed spin labeling.Single molecule mechanical probing of the SNARE protein interactions.Cross-linking of phospholipid membranes is a conserved property of calcium-sensitive synaptotagminsLoss of synaptotagmin IV results in a reduction in synaptic vesicles and a distortion of the Golgi structure in cultured hippocampal neuronsSingle-molecule studies of the neuronal SNARE fusion machinery.Phosphomimetic mutation of cysteine string protein-α increases the rate of regulated exocytosis by modulating fusion pore dynamics in PC12 cells.Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering.Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis.The fusion pores of Ca2+ -triggered exocytosisSynaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusionRegulation of exocytosis and fusion pores by synaptotagmin-effector interactions.Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission.Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granulesSynaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor.Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs.Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.The SNARE complex in neuronal and sensory cells.Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex.Synaptotagmin I regulates patterned spontaneous activity in the developing rat retina via calcium binding to the C2AB domains.Inhibition of Ca2+ channels and adrenal catecholamine release by G protein coupled receptors.G protein betagamma-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties.Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin ISynaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.Mechanism and function of synaptotagmin-mediated membrane apposition.The role of Snapin in neurosecretion: snapin knock-out mice exhibit impaired calcium-dependent exocytosis of large dense-core vesicles in chromaffin cellsThe synaptotagmins: calcium sensors for vesicular trafficking.
P2860
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P2860
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
@en
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
@nl
type
label
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
@en
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
@nl
prefLabel
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
@en
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.
@nl
P50
P1433
P1476
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions
@en
P2093
Jihong Bai
Meyer B Jackson
P304
P356
10.1016/S0896-6273(04)00117-5
P407
P577
2004-03-01T00:00:00Z