Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis.
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Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibitionRole of EPAC in cAMP-Mediated Actions in Adrenocortical CellsActivation of focal adhesion kinase and JNK contributes to the extracellular matrix and cAMP-GEF mediated survival from bile acid induced apoptosis in rat hepatocytesSynergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells.Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Akt-mediated signaling is induced by cytokines and cyclic adenosine monophosphate and suppresses hepatocyte inducible nitric oxide synthase expression independent of MAPK P44/42.Calcium-mediated signaling and calmodulin-dependent kinase regulate hepatocyte-inducible nitric oxide synthase expression.Protein kinase Cδ protects against bile acid apoptosis by suppressing proapoptotic JNK and BIM pathways in human and rat hepatocytes.Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinaseInsulin inhibits hepatocyte iNOS expression induced by cytokines by an Akt-dependent mechanism.Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.cAMP-GEF cytoprotection by Src tyrosine kinase activation of phosphoinositide-3-kinase p110 beta/alpha in rat hepatocytesRolipram attenuates bile duct ligation-induced liver injury in rats: a potential pathogenic role of PDE4Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors.Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells.Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinomaDopamine regulation of amiloride-sensitive sodium channels in lung cells.The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation ofInhibition of ATP release from erythrocytes: a role for EPACs and PKC.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma
P2860
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P2860
Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis.
description
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name
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@en
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@nl
type
label
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@en
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@nl
prefLabel
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@en
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@nl
P2093
P2860
P356
P1476
Activation of cAMP-guanine exc ...... ion from hepatocyte apoptosis.
@en
P2093
Cynthia R L Webster
John McCool
Kimberly A Cullen
M Sawkat Anwer
P2860
P304
P356
10.1152/AJPGI.00517.2003
P577
2004-03-25T00:00:00Z