Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred.
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Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patientsInteractions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer.MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations.Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesisThe biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized careA review of the clinical relevance of mismatch-repair deficiency in ovarian cancerDNA replication fidelity and cancerExtracolonic manifestations of lynch syndromeMicrosatellite analysis of hereditary nonpolyposis colorectal cancer-associated colorectal adenomas by laser-assisted microdissection: correlation with mismatch repair protein expression provides new insights in early steps of tumorigenesisA procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer.Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families.Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.Genetic implications of double primary cancers of the colorectum and endometrium.Some aspects of molecular diagnostics in Lynch syndrome.Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions.Genetic susceptibility to non-polyposis colorectal cancer.Genomic and epigenetic instability in colorectal cancer pathogenesis.Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.DNA mismatch repair genes and colorectal cancer.Pedigree and genetic analysis of a novel mutation carrier patient suffering from hereditary nonpolyposis colorectal cancer.Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progressionHereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management.A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory.Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers.Mismatch repair proficiency and in vitro response to 5-fluorouracil.Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosisDNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.Microsatellite instability and the clinicopathological features of sporadic colorectal cancer.Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancerThe role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancersFrequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patientsAn insight into the genetic pathway of adenocarcinoma of the small intestineAssociation between family history and mismatch repair in colorectal cancer.Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1)Tumor microsatellite instability in early onset gastric cancerIs surveillance of the small bowel indicated for Lynch syndrome families?
P2860
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P2860
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@en
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@nl
type
label
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@en
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@nl
prefLabel
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@en
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@nl
P2093
P1433
P1476
Germ-line mutation of the hMSH ...... sis colorectal cancer kindred.
@en
P2093
Nagasaki H
Tsuchiya A
P304
P407
P577
1997-09-01T00:00:00Z