Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.
about
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiationThe transcription factor PLZF directs the effector program of the NKT cell lineageRole of the transcription factor Bcl11b in development and lymphomagenesisTranscriptional control of CD4 and CD8 coreceptor expression during T cell developmentDistinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cellsThe transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gammaItk derived signals regulate the expression of Th-POK and controls the development of CD4 T cells.Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus.TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cellsCo-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection.Runt-related transcription factor 3 is involved in the altered phenotype and function in ThPok-deficient invariant natural killer T cellsThe leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes.Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation.The microRNA biogenesis machinery modulates lineage commitment during αβ T cell development.A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.Transcriptional repressors, corepressors and chromatin modifying enzymes in T cell development.Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.Transcription factor T-bet regulates intraepithelial lymphocyte functional maturation.Aryl hydrocarbon receptor promotes RORγt⁺ group 3 ILCs and controls intestinal immunity and inflammation.Runx3-mediated transcriptional program in cytotoxic lymphocytes.Transcriptional and epigenetic networks of helper T and innate lymphoid cells.Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory.Signal transduction pathways and transcriptional regulation in Th17 cell differentiationRUNX transcription factors: association with pediatric asthma and modulated by maternal smoking.TOX is required for development of the CD4 T cell lineage gene program.Coreceptor gene imprinting governs thymocyte lineage fate.Transcriptional Auto-Regulation of RUNX1 P1 Promoter.Restriction of Nonpermissive RUNX3 Protein Expression in T Lymphocytes by the Kozak Sequence.Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell developmentThe zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.CD4-CD8 lineage differentiation: Thpok-ing into the nucleus.Decision checkpoints in the thymus.The enigma of CD4-lineage specification.Critical role of P1-Runx1 in mouse basophil development.The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells.In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues.
P2860
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P248
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P2860
Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Repression of the transcriptio ...... cytotoxic T cell development.
@en
Repression of the transcriptio ...... cytotoxic T cell development.
@nl
type
label
Repression of the transcriptio ...... cytotoxic T cell development.
@en
Repression of the transcriptio ...... cytotoxic T cell development.
@nl
prefLabel
Repression of the transcriptio ...... cytotoxic T cell development.
@en
Repression of the transcriptio ...... cytotoxic T cell development.
@nl
P2093
P2860
P921
P356
P1433
P1476
Repression of the transcriptio ...... n cytotoxic T cell development
@en
P2093
Chieko Tezuka
Ichiro Taniuchi
Kaori Akiyama
Ruka Setoguchi
Sawako Muroi
Tsukasa Okuda
Yoshinori Naoe
P2860
P304
P356
10.1126/SCIENCE.1151844
P407
P577
2008-02-01T00:00:00Z