Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
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Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signalingHepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcriptionMenin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chainA human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control geneThe 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor geneCharacterization of mutations in patients with multiple endocrine neoplasia type 1.Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locusInherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversiesLocalization of the photoreceptor gene ROM1 to human chromosome 11 and mouse chromosome 19: sublocalization to human 11q13 between PGA and PYGMFamilial gigantismMEN1, MEN4, and Carney Complex: Pathology and Molecular GeneticsMenin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23Antioncogenes and human cancer.Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphismsIdentification and characterization of the multiple endocrine neoplasia type 1 (MEN1) geneGermline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1)Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)MEN1 tumor-suppressor protein localizes to telomeres during meiosisMenin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4cMenin prevents liver steatosis through co-activation of peroxisome proliferator-activated receptor alphaReduction of menin expression enhances cell proliferation and is tumorigenic in intestinal epithelial cellsA mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumorsMenin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitusMapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14Clinicopathological characteristics and non-adhesive organ culture of insulinomas.Molecular genetic aspects of human cancers: the 1993 Frank Rose Lecture.Recessive mechanisms of malignancy.Molecular mechanisms of cancer.Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancersLoss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7.Distal deletion of chromosome Ip in ductal carcinoma of the breast.MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas.Epidemiology data on 108 MEN 1 patients from the GTE with isolated nonfunctioning tumors of the pancreas.Isolation and mapping of 62 new RFLP markers on human chromosome 11.Molecular markers of paragangliomas/pheochromocytomasGenetic studies of thymic carcinoids in multiple endocrine neoplasia type 1Identification of five novel germline mutations of the MEN1 gene in Japanese multiple endocrine neoplasia type 1 (MEN1) families.
P2860
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P2860
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@en
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@nl
type
label
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@en
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@nl
prefLabel
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@en
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@nl
P2093
P356
P1433
P1476
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
@en
P2093
P2888
P356
10.1038/332085A0
P407
P577
1988-03-01T00:00:00Z
P6179
1042110245